Department of Medical Sciences, University of Wisconsin-Madison School of Veterinary Medicine, Madison, Wisconsin, USA.
Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, USA.
J Vet Intern Med. 2024 Jul-Aug;38(4):2358-2361. doi: 10.1111/jvim.17104. Epub 2024 May 13.
To describe the diagnosis and successful treatment of systemic francisellosis in a dog. An 11-year-old female spayed Labrador retriever presented for progressive lethargy, hyporexia, and cough. The dog was febrile with a neutrophilia, nonregenerative anemia, thrombocytopenia, and had increased activity in serum of liver-derived enzymes. Francisella philomiragia was isolated from aerobic blood culture. The dog was treated for 6 weeks with enrofloxacin orally. Repeated aerobic blood cultures after 2 and 6 weeks of antibiotic therapy were negative. The dog was clinically normal 7 months after diagnosis with no evidence of relapse.
描述一只犬的全身性弗朗西斯菌病的诊断和成功治疗。一只 11 岁雌性去势拉布拉多猎犬因进行性嗜睡、食欲减退和咳嗽而就诊。该犬发热，伴有中性粒细胞增多、再生障碍性贫血、血小板减少，以及血清中转氨酶活性升高。从需氧血培养中分离出嗜沫弗朗西斯菌。该犬经口给予恩诺沙星治疗 6 周。在抗生素治疗 2 周和 6 周后重复进行需氧血培养均为阴性。在诊断后 7 个月，该犬临床状况正常，无复发迹象。
