Bernard O, Alvarez F, Alagille D
Arch Fr Pediatr. 1985 Mar;42(3):249-53.
A surgical porto-systemic shunt was carried out in 37 children and adolescents (age: 2 yrs-18 yrs) who presented with cirrhosis and portal hypertension. All patients were classified "A" or "B" according to Child's criteria. Proof of the patency of the shunt was obtained by endoscopy and/or angiography in 31 children. Two children died in the early postoperative period. Thrombosis of the shunt occurred in 4 children. With a follow-up of 6 months to 11 years, none of the 31 children operated on successfully presented with gastro-intestinal bleeding due to portal hypertension. Nine presented with one or several episodes of porto-systemic encephalopathy. Five of these were transient allowing for a normal diet to be resumed later. These results indicate that porto-systemic shunts are effective to prevent gastro-intestinal bleeding, even in young children with cirrhosis. However, in addition to Child's criteria, indications for shunt surgery must take into account the degree of hemorrhage risk and the possible need for a liver transplantation later.
对37例患有肝硬化和门静脉高压的儿童及青少年(年龄2岁至18岁)实施了外科门体分流术。所有患者均根据Child标准分为“A”或“B”级。通过内镜检查和/或血管造影术证实31例儿童的分流管通畅。2例儿童在术后早期死亡。4例儿童出现分流管血栓形成。随访6个月至11年,成功接受手术的31例儿童中,无1例因门静脉高压出现胃肠道出血。9例出现1次或数次门体性脑病发作。其中5例为短暂性发作,随后可恢复正常饮食。这些结果表明,门体分流术即使对患有肝硬化的幼儿也能有效预防胃肠道出血。然而,除了Child标准外,分流手术的指征还必须考虑出血风险程度以及后期可能需要进行肝移植的情况。