Diagnostic and Interventional Radiology, Heinrich-Heine-Universitat Düsseldorf, Düsseldorf, Germany.
Rofo. 2024 Dec;196(12):1236-1245. doi: 10.1055/a-2288-5743. Epub 2024 May 13.
Osteoarthritis (OA) is a chronic degenerative disease significantly impacting both patient quality of life and socioeconomics. Traditional treatment options, including pharmacological and surgical interventions, are often limited. Advancements in our understanding of the pathological mechanisms behind OA indicate the involvement of pathological angiogenesis. Transarterial microembolization (TAME), a minimally invasive radiological procedure, may present an innovative therapeutic approach. This review aims to consolidate current knowledge and experiences regarding TAME as a therapeutic modality for alleviating chronic joint pain associated with OA. It explores the role of TAME, focusing on its indications, patient selection, clinical outcomes, and future perspectives. Potential complications and associated risks are systematically addressed, alongside proposed strategies for risk mitigation and effective management.The presented patient cases originate from our institution, supplemented by a thorough review of relevant literature retrieved from PubMed.TAME represents a promising therapeutic approach, providing relief from the burden of joint diseases and substantially enhancing patient quality of life. Clinical outcomes emphasize the efficacy and safety of TAME in mitigating pain and improving functional capabilities in patients with chronic joint pain associated with OA. With mounting evidence of its therapeutic benefits and applicability to numerous joint-related pathologies, TAME offers a valuable addition to the arsenal of treatments for these conditions. · TAME is an innovative therapy for treating chronic joint pain related to OA.. · TAME is a technically challenging minimally invasive intervention requiring a high level of expertise.. · Understanding the challenges and complications of TAME can reduce risk and enhance procedural outcomes.. · Wilms LM, Jannusch K, Weiss D et al. Transarterial microembolization for the management of refractory chronic joint pain in osteoarthritis. Fortschr Röntgenstr 2024; DOI 10.1055/a-2288-5743.
骨关节炎(OA)是一种慢性退行性疾病,严重影响患者的生活质量和社会经济。传统的治疗选择,包括药物和手术干预,往往是有限的。我们对 OA 背后病理机制的理解的进步表明病理性血管生成的参与。经动脉微栓塞(TAME)是一种微创放射学程序,可能提供一种创新的治疗方法。本综述旨在整合 TAME 作为缓解与 OA 相关的慢性关节疼痛的治疗方法的现有知识和经验。它探讨了 TAME 的作用,重点关注其适应症、患者选择、临床结果和未来展望。系统地解决了潜在的并发症和相关风险,以及提出的风险缓解和有效管理策略。提出的病例来自我们的机构,并辅以从 PubMed 检索到的相关文献的全面审查。TAME 代表了一种有前途的治疗方法,为缓解关节疾病的负担和显著提高患者的生活质量提供了帮助。临床结果强调了 TAME 在减轻疼痛和改善慢性 OA 相关关节疼痛患者的功能能力方面的疗效和安全性。随着其治疗益处和对多种关节相关疾病的适用性的证据不断增加,TAME 为这些疾病的治疗提供了有价值的补充。· TAME 是治疗与 OA 相关的慢性关节疼痛的创新疗法。· TAME 是一种具有挑战性的微创介入技术,需要高度的专业知识。· 了解 TAME 的挑战和并发症可以降低风险并提高手术结果。· Wilms LM, Jannusch K, Weiss D 等人。经动脉微栓塞治疗骨关节炎难治性慢性关节痛。Fortschr Röntgenstr 2024;DOI 10.1055/a-2288-5743。