Kovbasiuk S A, Iudin V M, Kravchenko S P
Eksp Onkol. 1985;7(2):67-70.
A comparative morphofunctional analysis of lymphoid cells of BALB/c mice with the transplantable tumours was performed after the cyclophosphamide (CP) treatment. CP was injected by 3 schemes in a dose of 200 mg/kg of body weight. It was found that the more effective therapeutic scheme of CP treatment is accompanied by essential normalization of the ratio of lymphocyte populations in the lymph nodes against a background of a comparatively good state of proliferating cells as well as by a higher rate of restoration of proliferative responses to T and B cell mitogens in vivo.
对环磷酰胺（CP）处理后的BALB/c小鼠可移植肿瘤的淋巴细胞进行了比较形态功能分析。CP按3种方案以200mg/kg体重的剂量注射。结果发现，CP治疗更有效的方案伴随着淋巴结中淋巴细胞群体比例在增殖细胞相对良好状态的背景下基本恢复正常，以及体内对T和B细胞有丝分裂原的增殖反应恢复率更高。
