Research Unit of General Practice, Department of Public Health, University of Southern Denmark, Odense, Denmark.
BMC Geriatr. 2024 May 13;24(1):421. doi: 10.1186/s12877-024-04970-x.
Sarcopenia and sarcopenic obesity (SO) are age-related syndromes that may compromise physical and mental health among older adults. The Nordic countries differ from other regions on prevalence of disease, life-style behavior, and life expectancy, which may impact prevalence of sarcopenia and SO. Therefore, the aim of this study is to review the available evidence and gaps within this field in the Nordic countries.
PubMed, Embase, and Web of science (WOS) were searched up to February 2023. In addition, grey literature and reference lists of included studies were searched. Two independent researcher assessed papers and extracted data.
Thirty-three studies out of 6,363 searched studies were included in this scoping review. Overall prevalence of sarcopenia varied from 0.9 to 58.5%. A wide prevalence range was still present for community-dwelling older adults when definition criteria and setting were considered. The prevalence of SO ranged from 4 to 11%, according to the only study on this field. Based on the included studies, potential risk factors for sarcopenia include malnutrition, low physical activity, specific diseases (e.g., diabetes), inflammation, polypharmacy, and aging, whereas increased levels of physical activity and improved dietary intake may reduce the risk of sarcopenia. The few available interventions for sarcopenia were mainly focused on resistance training with/without nutritional supplements (e.g., protein, vitamin D).
The findings of our study revealed inadequate research on SO but an increasing trend in the number of studies on sarcopenia. However, most of the included studies had descriptive cross-sectional design, small sample size, and applied different diagnostic criteria. Therefore, larger well-designed cohort studies that adhere to uniform recent guidelines are required to capture a full picture of these two age-related medical conditions in Nordic countries, and plan for prevention/treatment accordingly.
肌少症和肌少症性肥胖(SO)是与年龄相关的综合征,可能会影响老年人的身心健康。北欧国家在疾病流行、生活方式行为和预期寿命方面与其他地区存在差异,这可能会影响肌少症和 SO 的流行率。因此,本研究旨在综述北欧国家在这一领域的现有证据和差距。
检索了 PubMed、Embase 和 Web of science(WOS),检索时间截至 2023 年 2 月。此外,还检索了纳入研究的灰色文献和参考文献列表。两名独立的研究人员评估了论文并提取了数据。
在 6363 篇搜索到的研究中,有 33 篇研究被纳入本范围综述。总体而言,肌少症的患病率从 0.9%到 58.5%不等。当考虑定义标准和研究背景时,社区居住的老年人的患病率范围仍然很广。根据唯一一项关于这一领域的研究,SO 的患病率为 4%至 11%。根据纳入的研究,肌少症的潜在危险因素包括营养不良、低体力活动、特定疾病(如糖尿病)、炎症、多药治疗和衰老,而增加体力活动和改善饮食摄入可能会降低肌少症的风险。为数不多的肌少症干预措施主要集中在抗阻训练加/不加营养补充剂(如蛋白质、维生素 D)上。
我们的研究结果表明,SO 的研究不足,但关于肌少症的研究数量呈上升趋势。然而,大多数纳入的研究都是描述性的横断面设计,样本量小,并且应用了不同的诊断标准。因此,需要进行更大规模、设计良好的队列研究,以充分了解北欧国家这两种与年龄相关的疾病,并相应地进行预防/治疗。