Nusrath Syed, Raju Kalidindi Venkata Vijaya Narsimha, Nekkanti Sri Siddhartha, Basudhe Madhunarayana, Thammineedi Subramanyeshwar Rao
Department of Surgical Oncology, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, Telangana 500034 India.
Indian J Surg Oncol. 2024 Jun;15(2):355-358. doi: 10.1007/s13193-024-01891-4. Epub 2024 Feb 12.
Gastric conduit necrosis is a rare but severe complication of esophageal surgery, often associated with mediastinal sepsis and high morbidity and mortality rates, as well as reduced efficacy of conservative treatments. In most cases, management involves salvage therapy, including fluid resuscitation, antibiotics, aggressive debridement, drainage of infected collections, and proximal esophageal diversion. Primary anastomosis is rarely performed. We describe a successful case wherein we salvaged a patient following a McKeown esophagectomy and gastric pull-up, who developed partial full-thickness necrosis of the gastric conduit postoperatively, along with pleural and mediastinal sepsis. We managed this situation through thoracic debridement, take-down of the anastomosis, resection of the devitalized segment of the conduit, and primary esophagogastric anastomosis. Conduit perfusion was demonstrated using ICG fluorescent angiography. This case illustrates that, once debridement and sepsis control are achieved, a primary anastomosis, if feasible, can be safely performed, potentially avoiding a two-step procedure and a second laparotomy/thoracotomy.
胃代食管坏死是食管手术罕见但严重的并发症,常伴有纵隔感染及高发病率和死亡率,以及保守治疗效果降低。在大多数情况下,治疗包括挽救性治疗,如液体复苏、抗生素、积极清创、引流感染灶以及近端食管转流。很少进行一期吻合术。我们描述了一例成功病例,一名患者在接受麦克尤恩食管切除术和胃上提术后,胃代食管出现部分全层坏死,并伴有胸膜和纵隔感染,我们通过胸腔清创、拆除吻合口、切除代食管失活段并进行一期食管胃吻合术对该情况进行了处理。使用吲哚菁绿荧光血管造影术证实了代食管灌注。该病例表明,一旦实现清创和控制感染,若可行,可安全地进行一期吻合术,有可能避免两步手术和二次剖腹/开胸手术。