麦胚凝集素激活巨噬细胞，使其与B细胞协作。
Wheat germ agglutinin activates macrophages for collaboration with B cells.
作者信息
Bernabé R R, Martinez-Alonso C, Larsson E L, Coutinho A
出版信息
Eur J Immunol. 1979 Aug;9(8):654-6. doi: 10.1002/eji.1830090816.
PMID:387424
Abstract
Wheat germ agglutinin (WGA), added to Mishell-Dutton-type cultures of nude spleen cells challenged with erythrocyte antigens, allows a primary specific plaque-forming cell (PFC) response. WGA, however, does not display direct mitogenicity to either T or B lymphocytes. The activity of WGA in the specific PFC response is macrophage-dependent and parallels a nonspecific PFC response in the same cultures.
摘要
将小麦胚凝集素（WGA）添加到用红细胞抗原刺激的裸脾细胞的米舍尔-达顿氏型培养物中，可引发初次特异性空斑形成细胞（PFC）反应。然而，WGA对T淋巴细胞或B淋巴细胞均无直接促有丝分裂活性。WGA在特异性PFC反应中的活性依赖于巨噬细胞，且与同一培养物中的非特异性PFC反应相似。
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