Dental Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Research & Development, Farinroshaan Medical & Health Co. Ltd., Tehran, Iran.
Clin Oral Investig. 2024 May 14;28(6):310. doi: 10.1007/s00784-024-05660-z.
This systematic review and meta-analysis aimed to evaluate the prevalence of middle mesial canal (MMC) in permanent mandibular molars of different populations and regions based on cone-beam computed tomography (CBCT) studies.
PubMed, Scopus, Embase, Web of Science, and Open-Grey were searched up to October 2023 according to specific keywords. A hand search was conducted on the references of the included studies and articles from three peer-reviewed journals in endodontics. The main variable of interest was the prevalence of MMC. Additional data such as the total number of included cases, age and country of the population, CBCT device information, voxel size, and field of view details were also extracted. Extracted data were analyzed qualitatively with the JBI quality assessment checklist and quantitatively with STATA software.
Of 32,793 studied teeth, the cumulative prevalence of MMC in both mandibular 1 and 2 molars was 3.11% (95% CI: 2.00-4.44%). The subgroup analysis reveals a prevalence of 4.15% (95% CI: 2.69-5.89%) for mandibular 1 molars and 1.2% (95% CI: 0.2-2.83%) for mandibular 2 molars. The highest prevalence of MMC in 1 molar was attributed to South Asia (11.24%) and Africa (6.61%).
The prevalence of MMC varies among regions. Clinicians should be aware of the potential prevalence of MMC, particularly in mandibular first molars, as a missed MMC could result in endodontic failure.
The presence of MMCs varies in different geographic regions (0% to 29.7%). Clinicians should always look for MMC when doing an endodontic treatment on mandibular molars, as the presence of this canal is not uncommon. We suggest searching for this canal as if searching for the second mesiobuccal canal of maxillary 1st molars.
本系统评价和荟萃分析旨在基于锥形束计算机断层扫描（CBCT）研究评估不同人群和地区的恒下颌磨牙中间中根管（MMC）的患病率。
根据特定关键词，检索 PubMed、Scopus、Embase、Web of Science 和 Open-Grey，检索时间截至 2023 年 10 月。对手头研究和三本牙髓学同行评审期刊的文章的参考文献进行了手工搜索。主要关注的变量是 MMC 的患病率。还提取了总纳入病例数、人群年龄和国家、CBCT 设备信息、体素大小和视野详细信息等其他数据。使用 JBI 质量评估清单对提取的数据进行定性分析，并使用 STATA 软件进行定量分析。
在 32793 颗研究牙中，双侧下颌 1 号和 2 号磨牙 MMC 的累积患病率为 3.11%（95%CI：2.00-4.44%）。亚组分析显示下颌 1 号磨牙的患病率为 4.15%（95%CI：2.69-5.89%），下颌 2 号磨牙的患病率为 1.2%（95%CI：0.2-2.83%）。1 号磨牙中 MMC 患病率最高的地区是南亚（11.24%）和非洲（6.61%）。
MMC 的患病率在不同地区有所不同。临床医生应该意识到 MMC 的潜在患病率，特别是在下颌第一磨牙中，因为遗漏 MMC 可能导致根管治疗失败。
MMC 在不同地理区域的存在率（0%-29.7%）有所不同。当在下颌磨牙进行根管治疗时，临床医生应始终寻找 MMC，因为这种根管的存在并不罕见。我们建议像寻找上颌第一磨牙的第二近中颊根管一样搜索该根管。
