Structural and functional evidence that GPR30 is not a direct estrogen receptor.
作者信息
Liu Heng, Guo Shimeng, Dai Antao, Xu Peiyu, Li Xin, Huang Sijie, He Xinheng, Wu Kai, Zhang Xinyue, Yang Dehua, Xie Xin, Xu H Eric
机构信息
The State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
The State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
出版信息
Cell Res. 2024 Jul;34(7):530-533. doi: 10.1038/s41422-024-00963-y. Epub 2024 May 14.
Abstract
摘要
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Nat Rev Endocrinol. 2023 Jul;19(7):407-424. doi: 10.1038/s41574-023-00822-7. Epub 2023 May 16.
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Multiplex G Protein-Coupled Receptor Screen Reveals Reliably Acting Agonists and a Gq-Phospholipase C Coupling Mode of GPR30/GPER1.多重G蛋白偶联受体筛选揭示了GPR30/GPER1可靠起作用的激动剂和Gq-磷脂酶C偶联模式。
Mol Pharmacol. 2023 Feb;103(2):48-62. doi: 10.1124/molpharm.122.000580. Epub 2022 Nov 18.
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Role of estrogen receptors in health and disease.雌激素受体在健康和疾病中的作用。
Front Endocrinol (Lausanne). 2022 Aug 18;13:839005. doi: 10.3389/fendo.2022.839005. eCollection 2022.
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Mol Pharmacol. 2021 Sep;100(3):271-282. doi: 10.1124/molpharm.121.000259. Epub 2021 Jul 30.
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