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全麻下胸腔镜手术治疗老年患者术后肺部并发症的危险因素:一项回顾性研究。

Risk factors for postoperative pulmonary complications in elderly patients undergoing video-assisted thoracoscopic surgery lobectomy under general anesthesia: a retrospective study.

机构信息

Department of Anesthesiology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.

出版信息

BMC Surg. 2024 May 14;24(1):153. doi: 10.1186/s12893-024-02444-w.

DOI:10.1186/s12893-024-02444-w
PMID:38745149
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11091990/
Abstract

BACKGROUND

The objective of this study is to identify and evaluate the risk factors associated with the development of postoperative pulmonary complications (PPCs) in elderly patients undergoing video-assisted thoracoscopic surgery lobectomy under general anesthesia.

METHODS

The retrospective study consecutively included elderly patients (≥ 70 years old) who underwent thoracoscopic lobectomy at Xuanwu Hospital of Capital Medical University from January 1, 2018 to August 31, 2023. The demographic characteristics, the preoperative, intraoperative and postoperative parameters were collected and analyzed using multivariate logistic regression to identify the prediction of risk factors for PPCs.

RESULTS

322 patients were included for analysis, and 115 patients (35.7%) developed PPCs. Multifactorial regression analysis showed that ASA ≥ III (P = 0.006, 95% CI: 1.230 ∼ 3.532), duration of one-lung ventilation (P = 0.033, 95% CI: 1.069 ∼ 4.867), smoking (P = 0.027, 95% CI: 1.072 ∼ 3.194) and COPD (P = 0.015, 95% CI: 1.332 ∼ 13.716) are independent risk factors for PPCs after thoracoscopic lobectomy in elderly patients.

CONCLUSION

Risk factors for PPCs are ASA ≥ III, duration of one-lung ventilation, smoking and COPD in elderly patients over 70 years old undergoing thoracoscopic lobectomy. It is necessary to pay special attention to these patients to help optimize the allocation of resources and enhance preventive efforts.

摘要

背景

本研究旨在确定和评估与全身麻醉下接受电视辅助胸腔镜手术肺叶切除术的老年患者术后肺部并发症(PPCs)发展相关的风险因素。

方法

本回顾性研究连续纳入了 2018 年 1 月 1 日至 2023 年 8 月 31 日期间在中国首都医科大学宣武医院接受胸腔镜肺叶切除术的老年患者(≥70 岁)。收集并分析了人口统计学特征、术前、术中及术后参数,采用多变量逻辑回归分析来确定 PPCs 的预测风险因素。

结果

共纳入 322 例患者进行分析,其中 115 例(35.7%)发生 PPCs。多因素回归分析显示,ASA 分级≥III 级(P=0.006,95%CI:1.230~3.532)、单肺通气时间(P=0.033,95%CI:1.069~4.867)、吸烟史(P=0.027,95%CI:1.072~3.194)和 COPD(P=0.015,95%CI:1.332~13.716)是老年患者胸腔镜肺叶切除术后 PPCs 的独立危险因素。

结论

ASA 分级≥III 级、单肺通气时间、吸烟史和 COPD 是 70 岁以上老年患者接受胸腔镜肺叶切除术后发生 PPCs 的危险因素。对这些患者应特别关注,有助于优化资源配置并加强预防措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a514/11091990/2d145d02263b/12893_2024_2444_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a514/11091990/2d145d02263b/12893_2024_2444_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a514/11091990/2d145d02263b/12893_2024_2444_Fig1_HTML.jpg

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