Dontsov V I
Biull Eksp Biol Med. 1985 Jul;100(7):65-8.
It has been shown that in the course of isoproterenol induction of cell proliferation of rat and mouse salivary glands, there takes place formation of T lymphocytes that stimulate and inhibit proliferation of the gland cells. In the absence of T lymphocytes isoproterenol does not induce cell proliferation. It has been demonstrated in mice that lymphocytes that stimulate cell proliferation of the salivary glands belong to Ly 1+ T lymphocytes whereas those inhibiting proliferation to Ly 2+ T lymphocytes. The former ones are formed and proliferate before commencement of glandular cell proliferation, and the latter ones concurrently with the development of cell proliferation of the salivary glands. The mechanisms described may point to the existence of a special system of T lymphocytes, that is not identical to the immune system, with this special system playing a definite role in the maintenance of the proliferative homeostasis of host tissues.
业已表明，在异丙肾上腺素诱导大鼠和小鼠唾液腺细胞增殖的过程中，会形成刺激和抑制腺细胞增殖的T淋巴细胞。在缺乏T淋巴细胞的情况下，异丙肾上腺素不会诱导细胞增殖。在小鼠中已证实，刺激唾液腺细胞增殖的淋巴细胞属于Ly 1 + T淋巴细胞，而抑制增殖的淋巴细胞属于Ly 2 + T淋巴细胞。前者在腺细胞增殖开始之前形成并增殖，而后者在唾液腺细胞增殖发展的同时出现。所描述的这些机制可能表明存在一个特殊的T淋巴细胞系统，它与免疫系统不同，这个特殊系统在维持宿主组织的增殖稳态中发挥着一定作用。
