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声门下狭窄的治疗:单机构经验。

TREATMENT OF SUBGLOTTIC STENOSIS: A SINGLE INSTITUTION EXPERIENCE.

机构信息

Department of Otorhinolaryngology and Head and Neck Surgery, Zagreb University Hospital Center, Zagreb, Croatia.

School of Medicine, University of Zagreb, Zagreb, Croatia.

出版信息

Acta Clin Croat. 2023 Apr;62(Suppl1):42-48. doi: 10.20471/acc.2023.62.s1.05.

DOI:10.20471/acc.2023.62.s1.05
PMID:38746604
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11090229/
Abstract

The aim of this article is to present experiences of the Department of Otorhinolaryngology and Head and Neck Surgery, Zagreb University Hospital Center with the treatment of patients with subglottic stenosis. Subglottic stenosis is a rare congenital or acquired disorder of airway patency that is part of a wider complex of disorders known as laryngotracheal stenosis with the ultimate effect in the form of respiratory insufficiency that can be life-threatening. As an acquired condition, it is most often the result of iatrogenic damage to the larynx and trachea during invasive airway management, whether it is intubation or tracheotomy. In the case of intubation as the etiologic factor, cases of prolonged intubation were most common. Retrospective analysis of patient medical histories over a ten-year period was performed and 29 patients met the inclusion criteria. All patients were monitored for at least two years after completion of treatment. Out of a total of 29 treated patients, 20 were permanently decannulated, of which 4 have paresis of one or both vocal cords. In conclusion, there is no clear treatment protocol for patients with subglottic stenosis. The optimal modality of treatment is combined endoscopic and open surgical treatment.

摘要

本文旨在介绍萨格勒布大学医院耳鼻喉头颈外科在治疗声门下狭窄患者方面的经验。声门下狭窄是一种罕见的先天性或后天性气道通畅障碍,是更广泛的喉气管狭窄综合征的一部分,最终表现为呼吸功能不全,可能危及生命。作为后天性疾病,它最常因侵入性气道管理(无论是插管还是气管切开术)导致喉和气管的医源性损伤而发生。在插管作为病因的情况下,长时间插管的病例最为常见。对十年来的患者病史进行回顾性分析,符合纳入标准的患者共有 29 名。所有患者在治疗完成后至少随访两年。在总共 29 名接受治疗的患者中,20 名永久性拔管,其中 4 名患者出现单侧或双侧声带麻痹。总之,对于声门下狭窄患者,目前还没有明确的治疗方案。最佳的治疗方式是内镜联合开放手术治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4025/11090229/ebb9942e476e/acc-62_supp1-42-f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4025/11090229/09281a1fc79a/acc-62_supp1-42-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4025/11090229/e6aceb5413a9/acc-62_supp1-42-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4025/11090229/ec26ba89b41c/acc-62_supp1-42-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4025/11090229/ad6d24b0c23b/acc-62_supp1-42-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4025/11090229/b2ef38bb4b0f/acc-62_supp1-42-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4025/11090229/ebb9942e476e/acc-62_supp1-42-f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4025/11090229/09281a1fc79a/acc-62_supp1-42-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4025/11090229/e6aceb5413a9/acc-62_supp1-42-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4025/11090229/ec26ba89b41c/acc-62_supp1-42-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4025/11090229/ad6d24b0c23b/acc-62_supp1-42-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4025/11090229/b2ef38bb4b0f/acc-62_supp1-42-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4025/11090229/ebb9942e476e/acc-62_supp1-42-f6.jpg

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J Clin Nurs. 2024 Jan;33(1):6-10. doi: 10.1111/jocn.15992. Epub 2021 Aug 8.
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Tracheal Stenosis after Tracheostomy.气管切开术后气管狭窄。
Br J Oral Maxillofac Surg. 2021 Jan;59(1):82-85. doi: 10.1016/j.bjoms.2020.08.036. Epub 2020 Aug 19.
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Long-term intubation and high rate of tracheostomy in COVID-19 patients might determine an unprecedented increase of airway stenoses: a call to action from the European Laryngological Society.
在 COVID-19 患者中,长期插管和高气管切开率可能导致气道狭窄前所未有地增加:这是欧洲喉科学会发出的行动呼吁。
Eur Arch Otorhinolaryngol. 2021 Jan;278(1):1-7. doi: 10.1007/s00405-020-06112-6. Epub 2020 Jun 6.
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Endoscopic Treatment of Idiopathic Subglottic Stenosis: A Systematic Review.特发性声门下狭窄的内镜治疗:一项系统评价
Front Surg. 2020 Jan 10;6:75. doi: 10.3389/fsurg.2019.00075. eCollection 2019.
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Comparative Treatment Outcomes for Patients With Idiopathic Subglottic Stenosis.特发性声门下狭窄患者的治疗结果比较。
JAMA Otolaryngol Head Neck Surg. 2020 Jan 1;146(1):20-29. doi: 10.1001/jamaoto.2019.3022.
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Incidence and Outcomes of Acute Laryngeal Injury After Prolonged Mechanical Ventilation.长时间机械通气后急性喉损伤的发生率和结局。
Crit Care Med. 2019 Dec;47(12):1699-1706. doi: 10.1097/CCM.0000000000004015.
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The role of pepsin in epithelia-mesenchymal transition in idiopathic subglottic stenosis.胃蛋白酶在特发性声门下狭窄中上皮-间充质转化中的作用。
Laryngoscope. 2020 Jan;130(1):154-158. doi: 10.1002/lary.27879. Epub 2019 Feb 18.
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