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用于治疗癌症的新型CD73抑制剂

Novel CD73 Inhibitors for Treating Cancer.

作者信息

Sabnis Ram W

机构信息

Smith, Gambrell & Russell LLP, 1105 W. Peachtree Street NE, Suite 1000, Atlanta, Georgia 30309, United States.

出版信息

ACS Med Chem Lett. 2024 Apr 9;15(5):571-572. doi: 10.1021/acsmedchemlett.4c00137. eCollection 2024 May 9.

Abstract

Provided herein are novel CD73 inhibitors, pharmaceutical compositions, use of such compounds in treating cancer, and processes for preparing such compounds.

摘要

本文提供了新型CD73抑制剂、药物组合物、此类化合物在治疗癌症中的用途以及制备此类化合物的方法。

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本文引用的文献

1
Metabolic interplay: tumor macrophages and regulatory T cells.代谢相互作用:肿瘤巨噬细胞和调节性 T 细胞。
Trends Cancer. 2024 Mar;10(3):242-255. doi: 10.1016/j.trecan.2023.11.007. Epub 2023 Dec 22.
2
Small molecular CD73 inhibitors: Recent progress and future perspectives.小分子 CD73 抑制剂:最新进展与未来展望。
Eur J Med Chem. 2024 Jan 15;264:116028. doi: 10.1016/j.ejmech.2023.116028. Epub 2023 Dec 7.

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