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全胃切除术后双重转运重建在胃癌患者中的优势:系统评价。

ARE THERE ADVANTAGES IN DOUBLE TRANSIT RECONSTRUCTION AFTER TOTAL GASTRECTOMY IN PATIENTS WITH GASTRIC CANCER? A SYSTEMATIC REVIEW.

机构信息

Universidade Estadual de Campinas, Faculty of Medical Sciences, Postgraduate Program in Surgical Sciences - Campinas (SP), Brazil.

Universidade do Estado do Pará, Medical School - Marabá (PA), Brazil.

出版信息

Arq Bras Cir Dig. 2024 May 13;37:e1799. doi: 10.1590/0102-672020240006e1799. eCollection 2024.

Abstract

BACKGROUND

Curative treatment for gastric cancer involves tumor resection, followed by transit reconstruction, with Roux-en-Y being the main technique employed. To permit food transit to the duodenum, which is absent in Roux-en-Y, double transit reconstruction has been used, whose theoretical advantages seem to surpass the previous technique.

AIMS

To compare the clinical evolution of gastric cancer patients who underwent total gastrectomy with Roux-en-Y and double tract reconstruction.

METHODS

A systematic review was carried out on Web of Science, Scopus, EmbasE, SciELO, Virtual Health Library, PubMed, Cochrane, and Google Scholar databases. Data were collected until June 11, 2022. Observational studies or clinical trials evaluating patients submitted to double tract (DT) and Roux-en-Y (RY) reconstructions were included. There was no temporal or language restriction. Review articles, case reports, case series, and incomplete texts were excluded. The risk of bias was calculated using the Cochrane tool designed for randomized clinical trials.

RESULTS

Four studies of good methodological quality were included, encompassing 209 participants. In the RY group, there was a greater reduction in food intake. In the DT group, the decrease in body mass index was less pronounced compared to preoperative values.

CONCLUSIONS

The double tract reconstruction had better outcomes concerning body mass index and the time until starting a light diet; however, it did not present any advantages in relation to nutritional deficits, quality of life, and post-surgical complications.

摘要

背景

胃癌的治愈性治疗包括肿瘤切除,然后进行转流重建,Roux-en-Y 是主要采用的技术。为了使食物能够进入十二指肠转流,双转流重建已经被使用,其理论优势似乎超过了前一种技术。

目的

比较接受 Roux-en-Y 和双路重建的胃癌患者的临床转归。

方法

对 Web of Science、Scopus、EmbasE、SciELO、Virtual Health Library、PubMed、Cochrane 和 Google Scholar 数据库进行了系统综述。数据收集截至 2022 年 6 月 11 日。纳入评估接受双路(DT)和 Roux-en-Y(RY)重建的患者的观察性研究或临床试验。没有时间或语言限制。排除综述文章、病例报告、病例系列和不完整的文本。使用为随机临床试验设计的 Cochrane 工具计算偏倚风险。

结果

纳入了四项方法学质量较好的研究,共纳入 209 名参与者。在 RY 组中,食物摄入量的减少更大。在 DT 组中,与术前相比,体重指数的下降不那么明显。

结论

双路重建在体重指数和开始清淡饮食的时间方面有更好的结果;然而,在营养不足、生活质量和术后并发症方面,它并没有表现出任何优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb3c/11090104/3dc6c9a5ac66/0102-6720-abcd-37-e1799-fg01.jpg

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