du Moulin G C, Sherman I H, Hoaglin D C, Stottmeier K D
J Clin Microbiol. 1985 Jul;22(1):9-12. doi: 10.1128/jcm.22.1.9-12.1985.
We report a study of 1,953 patients whose laboratory records from 1972 through 1983 at the Massachusetts Mycobacteria Reference Laboratory indicated the isolation of Mycobacterium avium complex (MAC) organisms. At least one clinical specimen from each patient during this period exhibited the organism. The incidence of isolation of MAC has increased fivefold since 1972, with a doubling of the number of patients with positive MAC specimens from normally sterile sites occurring since 1980. A concomitant increase of more than fourfold in other nontuberculous mycobacteria has occurred. Most isolates came from high-density population centers. Communities whose drinking water comes from a distant rather than a local source were more likely to have patients with MAC.
我们报告了一项对1953例患者的研究，这些患者在1972年至1983年期间于马萨诸塞分枝杆菌参考实验室的实验室记录显示分离出鸟分枝杆菌复合群（MAC）微生物。在此期间，每位患者至少有一份临床标本检出该微生物。自1972年以来，MAC的分离率增加了五倍，自1980年以来，来自通常无菌部位的MAC标本呈阳性的患者数量翻了一番。其他非结核分枝杆菌也出现了四倍多的相应增加。大多数分离株来自高密度人口中心。饮用水来自远处而非本地水源的社区，其患者感染MAC的可能性更大。
