Ito Tetsuya, Tomizawa Emi, Yano Yuki, Akiyama Dai, Konishi Haruko, Takei Kiyozumi, Ikeda Masahiro, Takahashi Naoko, Shaku Fumio
Department of Palliative Medicine and Advanced Clinical Oncology, IMSUT Hospital, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan.
Department of Palliative Care, Japanese Red Cross Medical Center, Shibuya-ku, Tokyo, Japan.
Am J Hosp Palliat Care. 2025 Feb;42(2):172-177. doi: 10.1177/10499091241254522. Epub 2024 May 15.
Association between physical symptoms and psychosocial difficulties of cancer patients has been reported widely. Nevertheless, the effects of pain and other symptom control on anxiety in such patients have not been investigated well. We investigated the association of improvement of pain and other symptoms with patient anxiety, and assessed factors associated with improvement of such symptoms. Data of patients with advanced cancer admitted to a palliative care unit during August 2018 - June 2022 were analyzed retrospectively. Severity of pain, other symptoms, and anxiety was assessed by the Support Team Assessment Schedule Japanese version (STAS-J) administered at admission and after 2 weeks. Patients' physical data, their Palliative Prognostic Index (PPI) at admission, and their overall survival were collected and recorded. Data of 701 patients were analyzed. Improvement of pain or other symptoms after 2 weeks was not associated with the PPI total score or actual survival ( = .105 and .999). Patients with higher anxiety on admission experienced improvement of pain or other symptoms more frequently ( = .005). Worsening of anxiety was observed less in patients who experienced improvement in pain or other symptoms after 2 weeks ( = .027). Pain or other symptoms of patients with advanced cancer was improved irrespective of the general condition indicated with actual survival and prognosis-predictive factors. These findings suggest the importance of pain and other symptoms' improvement and its important roles in the management of patient psychosocial problems such as anxiety.
癌症患者身体症状与心理社会困难之间的关联已被广泛报道。然而，疼痛和其他症状控制对这类患者焦虑的影响尚未得到充分研究。我们调查了疼痛和其他症状改善与患者焦虑之间的关联，并评估了与这些症状改善相关的因素。对2018年8月至2022年6月期间入住姑息治疗病房的晚期癌症患者的数据进行了回顾性分析。通过入院时和2周后实施的日本版支持团队评估量表（STAS-J）评估疼痛、其他症状和焦虑的严重程度。收集并记录患者的身体数据、入院时的姑息预后指数（PPI）以及他们的总生存期。对701例患者的数据进行了分析。2周后疼痛或其他症状的改善与PPI总分或实际生存期无关（P = 0.105和0.999）。入院时焦虑程度较高的患者疼痛或其他症状改善的频率更高（P = 0.005）。在2周后疼痛或其他症状有所改善的患者中，焦虑加重的情况较少（P = 0.027）。晚期癌症患者的疼痛或其他症状得到改善，无论其实际生存期和预后预测因素所表明的一般状况如何。这些发现表明疼痛和其他症状改善的重要性及其在管理患者心理社会问题（如焦虑）中的重要作用。
