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一种新型催眠药(非诺加)与硝西泮和三氯福司钠的对比试验。

Comparative trial of a new hypnotic (Finorgal) with nitrazepam and triclofos sodium.

作者信息

Baiotti G

出版信息

J Int Med Res. 1979;7(5):383-6. doi: 10.1177/030006057900700509.

Abstract

Thirty patients complaining of insomnia were studied in a double-blind trial with crossover of Finorgal, nitrazepam and triclofos sodium. Finorgal given as a hypnotic produced similar results to nitrazepam and triclofos sodium in terms of induction of sleep, duration and quality of sleep, dream recall and morning 'hangover'. Reported side-effects were not serious and occurred less frequently in association with Finorgal treatment than with nitrazepam or triclofos sodium. Laboratory investigations gave no indication of the development of any drug toxicity during the three-week period of the trial.

摘要

在一项双盲试验中,对30名主诉失眠的患者使用氟硝西泮、硝西泮和三氯福司钠进行交叉研究。作为催眠药使用时,氟硝西泮在诱导睡眠、睡眠持续时间和质量、梦境回忆以及早晨“宿醉”方面产生了与硝西泮和三氯福司钠相似的结果。报告的副作用并不严重,与氟硝西泮治疗相关的副作用发生频率低于硝西泮或三氯福司钠。实验室检查未显示在试验的三周期间有任何药物毒性的迹象。

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