• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

The mechanism of induction of the microsomal drug hydroxylating system in rat liver by phenobarbital.

作者信息

Rees D E

出版信息

Gen Pharmacol. 1979;10(5):341-50. doi: 10.1016/0306-3623(79)90068-5.

DOI:10.1016/0306-3623(79)90068-5
PMID:387512
Abstract
摘要

相似文献

1
The mechanism of induction of the microsomal drug hydroxylating system in rat liver by phenobarbital.苯巴比妥诱导大鼠肝脏微粒体药物羟化系统的机制。
Gen Pharmacol. 1979;10(5):341-50. doi: 10.1016/0306-3623(79)90068-5.
2
Differential effects of phenobarbital and 3-methylcholanthrene on rat hepatic ribosomal precursor RNA.苯巴比妥和3-甲基胆蒽对大鼠肝脏核糖体前体RNA的不同作用
Biochem Pharmacol. 1977 May 15;26(10):955-61. doi: 10.1016/0006-2952(77)90474-9.
3
16 beta-hydroxylation of 4-androstene-3,17-dione in phenobarbital-pretreated rat liver microsomes.苯巴比妥预处理大鼠肝微粒体中4-雄烯-3,17-二酮的16β-羟基化作用
FEBS Lett. 1980 May 5;113(2):193-5. doi: 10.1016/0014-5793(80)80589-8.
4
Induction of liver microsomal cytochrome P450 in cynomolgus monkeys.食蟹猴肝脏微粒体细胞色素P450的诱导
Drug Metab Dispos. 1995 Jul;23(7):736-48.
5
Characterization of ketamine induction of hepatic microsomal drug metabolism.氯胺酮诱导肝微粒体药物代谢的特性
Biochem Pharmacol. 1977 Dec 15;26(24):2451-3. doi: 10.1016/0006-2952(77)90458-0.
6
Hydroxylation of 14-C-niflumic acid by phenobarbital-induced rat liver microsomes.
Drug Metab Dispos. 1975 Mar-Apr;3(2):96-103.
7
Effect of phenobarbital on methyl transfer between methylated drugs and hepatic microsomal phospholipids.苯巴比妥对甲基化药物与肝微粒体磷脂之间甲基转移的影响。
Toxicol Appl Pharmacol. 1975 Jun;32(3):577-86. doi: 10.1016/0041-008x(75)90122-2.
8
The effect of ascorbic acid deficiency on extrahepatic microsomal metabolism of drugs and carcinogens in the guinea pig.
J Pharmacol Exp Ther. 1977 Jun;201(3):527-33.
9
[Effect of aminazin, phenobarbital and their combination on the activity of the liver hydroxylase system and on their individual pharmacological effects].[氯丙嗪、苯巴比妥及其联合用药对肝脏羟化酶系统活性及其各自药理作用的影响]
Farmakol Toksikol. 1977 Jul-Aug;40(4):438-42.
10
Influence of partial hepatectomy on the induction of liver microsomal drug-metabolizing enzymes produced by phenobarbital. A biochemical and ultrastructural study.部分肝切除对苯巴比妥诱导产生的肝微粒体药物代谢酶的影响。一项生化与超微结构研究。
Lab Invest. 1970 Apr;22(4):329-38.

引用本文的文献

1
Induction by phenobarbital of the mRNA for a specific variant of rat liver microsomal cytochrome P-450.苯巴比妥诱导大鼠肝微粒体细胞色素P - 450特定变体的mRNA产生。
Biochem J. 1981 Jun 15;196(3):839-51. doi: 10.1042/bj1960839.
2
Stimulation of de novo synthesis of cytochrome P-450 by phenobarbital in primary nonproliferating cultures of adult rat hepatocytes.苯巴比妥对成年大鼠肝细胞原代非增殖培养物中细胞色素P-450从头合成的刺激作用。
Proc Natl Acad Sci U S A. 1982 May;79(9):2922-6. doi: 10.1073/pnas.79.9.2922.
3
Asymmetric distribution of cytochrome P-450 and NADPH--cytochrome P-450 (cytochrome c) reductase in vesicles from smooth endoplasmic reticulum of rat liver.
细胞色素P - 450和NADPH - 细胞色素P - 450（细胞色素c）还原酶在大鼠肝脏滑面内质网囊泡中的不对称分布。
Biochem J. 1980 Sep 15;190(3):737-46. doi: 10.1042/bj1900737.