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控制女性性行为的激素和回路机制。

Hormonal and circuit mechanisms controlling female sexual behavior.

机构信息

Department of Psychiatry, School of Medicine, Washington University in St. Louis, St. Louis, MO, United States.

出版信息

Front Neural Circuits. 2024 May 1;18:1409349. doi: 10.3389/fncir.2024.1409349. eCollection 2024.

DOI:10.3389/fncir.2024.1409349
PMID:38752168
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11094328/
Abstract

Sexual behavior is crucial for reproduction in many animals. In many vertebrates, females exhibit sexual behavior only during a brief period surrounding ovulation. Over the decades, studies have identified the roles of ovarian sex hormones, which peak in levels around the time of ovulation, and the critical brain regions involved in the regulation of female sexual behavior. Modern technical innovations have enabled a deeper understanding of the neural circuit mechanisms controlling this behavior. In this review, I summarize our current knowledge and discuss the neural circuit mechanisms by which female sexual behavior occurs in association with the ovulatory phase of their cycle.

摘要

性行为对许多动物的繁殖至关重要。在许多脊椎动物中,雌性只在排卵周围的短暂时期表现出性行为。几十年来,研究已经确定了卵巢性激素的作用,这些激素在排卵时达到高峰,以及参与调节雌性性行为的关键大脑区域。现代技术创新使我们能够更深入地了解控制这种行为的神经回路机制。在这篇综述中,我总结了我们目前的知识,并讨论了与雌性周期排卵阶段相关的雌性性行为发生的神经回路机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f14/11094328/c492ab95998d/fncir-18-1409349-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f14/11094328/e48fb6db77c2/fncir-18-1409349-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f14/11094328/c492ab95998d/fncir-18-1409349-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f14/11094328/e48fb6db77c2/fncir-18-1409349-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f14/11094328/c492ab95998d/fncir-18-1409349-g002.jpg

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Hormone-mediated neural remodeling orchestrates parenting onset during pregnancy.激素介导的神经重塑在怀孕期间调控着亲代行为的开始。
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