Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
J Adolesc Health. 2024 Jul;75(1):127-132. doi: 10.1016/j.jadohealth.2024.03.005. Epub 2024 May 14.
To evaluate differences in auxological parameters between transgender and cisgender adolescents.
Retrospective analysis of auxological data of 269 transgender and gender diverse patients (75% assigned female at birth or AFAB, 25% assigned male at birth or AMAB) at the outpatient clinic for Pediatric Endocrinology at the Vienna General Hospital. All were treatment naïve at initial measurement. Height and weight data were compared to current World Health Organization (WHO) standards, defining a standard deviation score (SDS) of ≥ 1 ≤ 2 as overweight and > 2 as obese.
In our untreated transgender population (mean age 15.7 years), 20% were overweight and 17% obese. Mean BMI was 0.64 SDS above the WHO average (p < .001). This result was more pronounced in the AFAB subgroup (+0.73 SDS, p < .001) than in the AMAB group (+0.37 SDS, p = .07). The AMAB group showed markedly higher BMI variance compared to WHO standards (p < .001) and to the AFAB group (p = .03), due to a higher relative number of underweight observations. When correcting for psychiatric diagnosis, transgender patients were still significantly overweight (p < .001). In patients for whom data both pregender-affirming hormone therapy and during gender-affirming hormone therapy was available (n = 133), BMI SDS did not change significantly over time (p = .22).
We observed significantly higher rates of overweight and obesity in our adolescent transgender cohort. The reasons are likely complex and multifactorial. This makes eating and exercise behaviors central in both transgender care and future research.
评估跨性别和顺性别青少年在生长参数方面的差异。
回顾性分析维也纳综合医院儿科内分泌门诊 269 名跨性别和性别多样化患者（75%出生时被指定为女性，即女性，25%出生时被指定为男性，即男性）的生长数据。所有患者在初始测量时均未接受治疗。将身高和体重数据与当前世界卫生组织（WHO）标准进行比较，将标准差评分（SDS）≥1≤2定义为超重，>2定义为肥胖。
在我们未治疗的跨性别人群中（平均年龄 15.7 岁），20%超重，17%肥胖。平均 BMI 比 WHO 平均值高 0.64 SDS（p<0.001）。在女性组中更为明显（+0.73 SDS，p<0.001），而在男性组中则不太明显（+0.37 SDS，p=0.07）。男性组与 WHO 标准（p<0.001）和女性组（p=0.03）相比，BMI 方差明显更高，这是由于相对较多的体重不足观察结果。当校正精神科诊断后，跨性别患者仍明显超重（p<0.001）。对于那些既有性别肯定前激素治疗又有性别肯定后激素治疗数据的患者（n=133），BMI SDS 随时间变化没有显著变化（p=0.22）。
我们观察到我们的青少年跨性别队列中超重和肥胖的发生率明显较高。原因可能是复杂和多因素的。这使得饮食和运动行为成为跨性别护理和未来研究的核心。
