Department of Thyroid Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Department of Thyroid Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Am J Otolaryngol. 2024 Sep-Oct;45(5):104358. doi: 10.1016/j.amjoto.2024.104358. Epub 2024 Apr 28.
This case series study investigated the outcomes of an innovative approach, ansa cervicalis nerve (ACN)-to-recurrent laryngeal nerve (RLN) low-tension anastomosis.
Patients who received laryngeal nerve anastomosis between May 2015 and September 2021 at the facility were enrolled. The inclusion criteria were patients with RLN dissection and anastomosis immediately during thyroid surgery. Exclusion criteria were cases with anastomosis other than cervical loop-RLN anastomosis or pronunciation recovery time > 6 months. Patients admitted before January 2020 were assigned to group A which underwent the conventional tension-free anastomosis, and patients admitted after January 2020 were group B and underwent the innovative low-tension anastomosis (Dong's method).
A total of 13 patients were included, 11 patients received unilateral surgery, and 2 underwent bilateral surgery. For patients who underwent unilateral anastomosis, group B had a significantly higher percentage of normal pronunciation via GRBAS scale (83.3 % vs. 0 %, p = 0.015) and voice handicap index (66.7 % vs. 0 %, p = 0.002), and shorter recovery time in pronunciation (median: 1-day vs. 4 months, p = 0.001) than those in group A after surgery.
ACNs-to-RLN low-tension anastomosis with a laryngeal segment ≤1 cm (Dong's method) significantly improves postoperative pronunciation and recovery time. The results provide clinicians with a new strategy for ACN -to-RLN anastomosis during thyroid surgery.
本病例系列研究旨在探讨一种创新方法(颈袢神经(ACN)-喉返神经(RLN)低张力吻合术)的治疗效果。
本研究纳入了 2015 年 5 月至 2021 年 9 月期间在该机构接受喉神经吻合术的患者。纳入标准为在甲状腺手术中同时进行 RLN 解剖和吻合的患者。排除标准为吻合术式非颈袢-RLN 吻合术或发音恢复时间>6 个月的患者。2020 年 1 月前入院的患者被分配至 A 组,行常规无张力吻合术,2020 年 1 月后入院的患者被分配至 B 组,行创新的低张力吻合术(董氏方法)。
共纳入 13 例患者,其中 11 例行单侧手术,2 例行双侧手术。对于行单侧吻合术的患者,B 组在 GRBAS 量表(83.3% vs. 0%,p=0.015)和嗓音障碍指数(66.7% vs. 0%,p=0.002)方面发音正常的比例显著更高,且发音恢复时间更短(中位数:1 天 vs. 4 个月,p=0.001)。
对于长度≤1cm 的 RLN(董氏方法)行 ACN-RLN 低张力吻合术可显著改善术后发音和恢复时间。这些结果为临床医生在甲状腺手术中进行 ACN-RLN 吻合术提供了一种新策略。