Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 West Baltimore Street, Room 480, Baltimore, MD 21201, USA; Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD, USA.
Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 West Baltimore Street, Room 480, Baltimore, MD 21201, USA; Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD, USA.
Pediatr Clin North Am. 2024 Jun;71(3):529-549. doi: 10.1016/j.pcl.2024.01.018. Epub 2024 Mar 12.
This article considers ethical considerations surrounding pediatric vaccine development for pandemic preparedness, examines some historical cases of pediatric vaccines developed during past smallpox, influenza, and 2019 coronavirus disease pandemics, and discusses the current state of vaccine development for pandemic preparedness, including vaccines against smallpox/mpox, influenza, anthrax, and Ebola that are included in the US Strategic National Stockpile and vaccines being developed against priority pathogens identified by the World Health Organization.
本文考虑了围绕儿科疫苗研发以应对大流行所涉及的伦理问题，考察了过去天花、流感和 2019 年冠状病毒病大流行期间研发儿科疫苗的一些历史案例，并讨论了当前大流行准备疫苗研发的现状，包括纳入美国战略国家储备的天花/猴痘、流感、炭疽和埃博拉疫苗，以及正在针对世界卫生组织确定的优先病原体开发的疫苗。
