Centre for Bacterial Resistance Biology, Imperial College London, London, UK.
Department of Biology, University of Oxford, Oxford, UK.
Trends Microbiol. 2024 Jul;32(7):622-623. doi: 10.1016/j.tim.2024.04.014. Epub 2024 May 15.
Phages and plasmids are discrete mobile genetic elements (MGEs) with critical roles in gene dissemination across bacteria but limited scope for exchanging DNA between them. By investigating recent gene-sharing events, Pfeifer and Rocha describe how the hybrid elements phage-plasmids (P-Ps) promote gene flow between MGE types and evolve into new ones.
噬菌体和质粒是具有离散移动遗传元件（MGEs）的细菌，在基因传播方面具有关键作用，但它们之间交换 DNA 的范围有限。通过研究最近的基因共享事件，Pfeifer 和 Rocha 描述了噬菌体-质粒（P-Ps）混合元件如何促进 MGE 类型之间的基因流动，并进化成新的元件。
