Liu Zirui, Hu Ruiming, Cao Huabin, Huang Peng, Yan Hui, Meng Puyan, Xiong Zhiwei, Dai Xueyan, Yang Fan, Wang Li, Qiu Qian, Yan Linjie, Zhang Tao
Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, China.
Jiangxi Engineering Research Center for Animal Health Products, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, China.
Front Vet Sci. 2024 May 2;11:1375852. doi: 10.3389/fvets.2024.1375852. eCollection 2024.
Jingmen tick virus (JMTV) is a newly identified segmented flavivirus that has been recognized in multiple hosts, such as humans, buffalos, bats, rodents, mosquitos and ticks. Various clinical cases and studies manifested that JMTV is a true arbovirus with wide host spectrum and showed potential threats toward public health. JMTV has been reported in multiple countries in Asia, Europe, Africa, and America. Moreover, wild boars serve as an important intermediary between humans and the wild ecological system. In China, it has been reported in nine provinces, while the prevalence and the distribution of JMTV in most regions including Jiangxi Province are still unknown. Thus, to profile the distribution of JMTV in Jiangxi Province, an epidemiological investigation was carried out from 2020 to 2022. In current study, 66 ticks were collected from 17 wild boars in Jiangxi Province. The results showed that 12 out of 66 ticks were JMTV positive, indicating JMTV is prevalent in ticks and boars in Jiangxi Province. The genome sequences of JMTV strain WY01 were sequenced to profile viral evolution of JMTV in China. Phylogenetic analysis divided JMTV strains into two genotypes, Group I and Group II. WY01 belongs to Group II and it shares the closest evolutionary relationship with the Japan strains rather than the strains from neighboring provinces in China suggesting that JMTV might have complex transmission routes. Overall, current study, for the first time, reported that JMTV is prevalent in Jiangxi Province and provided additional information concerning JMTV distribution and evolution in China.
荆门蜱病毒（JMTV）是一种新发现的分节段黄病毒，已在多种宿主中被识别，如人类、水牛、蝙蝠、啮齿动物、蚊子和蜱虫。各种临床病例和研究表明，JMTV是一种真正的虫媒病毒，宿主谱广泛，对公共卫生构成潜在威胁。JMTV已在亚洲、欧洲、非洲和美洲的多个国家被报道。此外，野猪是人类与野生生态系统之间的重要媒介。在中国，已有9个省份报道过该病毒，而包括江西省在内的大多数地区JMTV的流行情况和分布仍不清楚。因此，为了解JMTV在江西省的分布情况，于2020年至2022年进行了一项流行病学调查。在本研究中，从江西省的17头野猪身上采集了66只蜱虫。结果显示，66只蜱虫中有12只为JMTV阳性，表明JMTV在江西省的蜱虫和野猪中普遍存在。对JMTV毒株WY01的基因组序列进行测序，以了解中国JMTV的病毒进化情况。系统发育分析将JMTV毒株分为两个基因型，即I组和II组。WY01属于II组，与日本毒株的进化关系最为密切，而非中国邻近省份的毒株，这表明JMTV可能具有复杂的传播途径。总体而言，本研究首次报道JMTV在江西省普遍存在，并提供了有关JMTV在中国分布和进化的更多信息。
