Mir Nazir Ud Din, Hossain Sk Sakir, Biswas Shyam
Department of Chemistry, Indian Institute of Technology Guwahati, 781039, Assam, India.
Chem Asian J. 2024 Aug 1;19(15):e202400377. doi: 10.1002/asia.202400377. Epub 2024 Jun 26.
The monitoring and precise determination of pesticides and pharmaceutical drugs and their residues have become increasingly important in the field of food safety and water contamination issues. Herein, a fluorescent aluminium MOF-based sensor (1) was developed for the selective recognition of neonicotinoid insecticide dinotefuran and anti-Parkinson's drug entacapone. Guest-free MOF 1' exhibited ultra-fast response (<5 s) and ultra-low detection limits of 2.3 and 7.6 nM for dinotefuran and entacapone, which are lower than the previously reported MOF-based sensors. In the presence of other competitive analytes, great selectivity was achieved towards both analytes. The probe was recyclable up to five cycles. The sensing ability was explored towards entacapone in human serum, urine and dinotefuran in real soil, rice, honey samples, different fruits, vegetables, real water specimens and a wide range of pH media. A low-cost, handy MOF-based polymer thin-film composite (1'@PVDF-PVP) was developed for the on-site detection of dinotefuran and entacapone. Mechanistic studies involving analytical techniques and theoretical calculations suggested that FRET and PET are the probable reasons for entacapone sensing whereas IFE is responsible for dinotefuran detection. The entire work presents a low cost, multi-use photoluminescent sensor of entacapone and dinotefuran to address the environmental pollution.
在食品安全和水污染问题领域，农药、药品及其残留的监测和精确测定变得越来越重要。在此，开发了一种基于荧光铝金属有机框架的传感器（1），用于选择性识别新烟碱类杀虫剂呋虫胺和抗帕金森病药物恩他卡朋。无客体金属有机框架1'对呋虫胺和恩他卡朋表现出超快响应（<5秒）和超低检测限，分别为2.3和7.6 nM，低于先前报道的基于金属有机框架的传感器。在存在其他竞争性分析物的情况下，对这两种分析物都具有很高的选择性。该探针可循环使用多达五个周期。研究了该传感器在人血清、尿液中对恩他卡朋以及在实际土壤、大米、蜂蜜样品、不同水果、蔬菜、实际水样和广泛pH介质中对呋虫胺的传感能力。开发了一种低成本、便于携带的基于金属有机框架的聚合物薄膜复合材料（1'@PVDF-PVP），用于现场检测呋虫胺和恩他卡朋。涉及分析技术和理论计算的机理研究表明，荧光共振能量转移（FRET）和光致电子转移（PET）是恩他卡朋传感的可能原因，而分子内电荷转移（IFE）负责呋虫胺的检测。整个工作展示了一种低成本、多用途的恩他卡朋和呋虫胺光致发光传感器，以解决环境污染问题。
