Sukh Hospital, Sri Muktsar Sahib, Punjab 152026, India.
Department of Psychiatry, Command Hospotal, Chandimandir, India.
Natl Med J India. 2023 Sep-Oct;36(5):286-290. doi: 10.25259/NMJI_170_21.
Background Infertility and its treatment are frequently associated with psychological distress. We assessed the prevalence of anxiety and depression in couples undergoing treatment for infertility with assisted reproductive techniques (ARTs). Methods We included 160 married couples undergoing treatment for infertility at an ART centre. The prevalence of anxiety and depression was assessed using the hospital anxiety and depression scale. Results The prevalence of anxiety and depression was 46.2% and 40.9%, respectively. Women had higher mean (SD) anxiety (10.76 [2.69]) and depression (9.86 [2.06]) scores; however, this gender difference was statistically significant only with respect to anxiety (p=0.02). The mean anxiety scores were highest among both genders when the cause of infertility was attributed to both partners and during the first year and 10 years after treatment. Men in the age groups of 20-24 years and 40-44 years and those with no prior treatment had a statistically significant association with the highest anxiety scores. The mean depression scores showed a statistically significant decline in both genders with increasing age. Among men, the mean depression scoreswere significantly higher in those with no prior treatment, male cause of infertility and during the first year and after 10 years of treatment. Conclusion The prevalence of anxiety and depression among infertile couples undergoing treatment with ART was almost twice as high as that in the general population. The mean anxiety scores were significantly associated with duration of treatment and gender-based attribution in both genders; however, age and prior treatment were associated with only men. The mean scores of depression were significantly associated with age in both genders, while duration of treatment, gender-based attribution and prior treatment were significantly associated only with men.
不孕及其治疗常与心理困扰相关。我们评估了接受辅助生殖技术（ART）治疗的不孕夫妇中焦虑和抑郁的患病率。
我们纳入了在一家 ART 中心接受不孕治疗的 160 对已婚夫妇。采用医院焦虑抑郁量表评估焦虑和抑郁的患病率。
焦虑和抑郁的患病率分别为 46.2%和 40.9%。女性的焦虑（10.76 [2.69]）和抑郁（9.86 [2.06]）评分均值更高；然而，这种性别差异仅在焦虑方面具有统计学意义（p=0.02）。当不孕的原因归咎于双方且处于治疗后的第 1 年和第 10 年时，两性的焦虑评分均值均最高。20-24 岁和 40-44 岁的男性以及无既往治疗的男性与最高的焦虑评分有统计学显著关联。两性的抑郁评分均值均随年龄增加而呈统计学显著下降。在男性中，无既往治疗、男性原因导致不孕以及治疗后的第 1 年和第 10 年，抑郁评分均值显著更高。
接受 ART 治疗的不孕夫妇中焦虑和抑郁的患病率几乎是一般人群的两倍。焦虑评分均值与两性的治疗持续时间和归因具有显著关联；然而，年龄和既往治疗仅与男性相关。抑郁评分均值与两性的年龄显著相关，而治疗持续时间、归因和既往治疗仅与男性显著相关。
