Department of Orthopedic Surgery, Fuyang People's Hospital, Anhui Medical University, 501, Sanqing Road, Fuyang, 236000, China.
Department of Hepatobiliary and Pancreatic Surgery, Fuyang People's Hospital, Anhui Medical University, Fuyang, 236000, China.
Arch Orthop Trauma Surg. 2024 Jun;144(6):2731-2743. doi: 10.1007/s00402-024-05250-4. Epub 2024 May 18.
To describe the disease burden of knee osteoarthritis (KOA) globally, regionally, and in 204 countries by age, sex, and sociodemographic index (SDI) from 1990 to 2019, and to explore cross-national inequalities across SDI.
The Global Burden of Disease (GBD) 2019 database collected data on KOA worldwide from 1990 to 2019, including prevalence, incidence, years lived with disability (YLDs). The average annual percentage change (AAPC) was used to measure temporal trends. In addition, the inequality slope index and the health concentration index were calculated to quantify the unequal distribution of the burden of KOA across 204 countries worldwide.
In 2019, the global age-standardized prevalence rate increased by 7.5% compared with 1990, and the age-standardized incidence rate increased by about 6.2%; The age-standardized YLDs rate increased by about 7.8%. In addition to the Republic of Korea and the United States of America, the disease burden of KOA has increased year by year in other countries around the world. The incidence of KOA was highest at ages 50-59, while the prevalence and rates of YLDs were highest at ages 75-84. The burden of KOA was higher in women than in men. Cross-country inequality suggests that the inequality in the burden of KOA between high SDI and low SDI countries becomes greater, and that countries with high SDI bear a disproportionately high burden.
The global KOA burden has risen steadily between 1990 and 2019, and cross-national inequality gaps remain large. Targeted measures must therefore be taken to address this inequality and the increasing global KOA disease burden.
描述 1990 年至 2019 年全球、区域和 204 个国家按年龄、性别和社会人口指数（SDI）划分的膝关节骨关节炎（KOA）疾病负担，并探讨 SDI 之间的跨国不平等。
使用 2019 年全球疾病负担（GBD）数据库收集全球范围内 KOA 的数据，包括患病率、发病率、残疾生活年（YLDs）。使用平均年百分比变化（AAPC）来衡量时间趋势。此外，还计算了不平等斜率指数和健康集中指数，以量化全球 204 个国家 KOA 负担的不平等分布。
2019 年，与 1990 年相比，全球年龄标准化患病率增加了 7.5%，年龄标准化发病率增加了约 6.2%；年龄标准化 YLDs 率增加了约 7.8%。除韩国和美利坚合众国外，世界其他国家的 KOA 疾病负担也在逐年增加。KOA 的发病率在 50-59 岁时最高，而患病率和 YLDs 率在 75-84 岁时最高。KOA 的负担在女性中高于男性。跨国不平等表明，高 SDI 和低 SDI 国家之间 KOA 负担的不平等程度越来越大，高 SDI 国家承担的负担不成比例地高。
1990 年至 2019 年期间，全球 KOA 负担稳步上升，跨国不平等差距仍然很大。因此，必须采取有针对性的措施来解决这一不平等和日益增加的全球 KOA 疾病负担。
