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人工智能辅助早期肿瘤标志物诊断及其应用

Artificial intelligence assisted diagnosis of early tc markers and its application.

作者信息

Zhang Laney, Wong Chinting, Li Yungeng, Huang Tianyi, Wang Jiawen, Lin Chenghe

机构信息

Yale School of Public Health, New Haven, CT, USA.

Department of Nuclear Medicine, The First Hospital of Jilin University, Changchun, Jilin, China.

出版信息

Discov Oncol. 2024 May 18;15(1):172. doi: 10.1007/s12672-024-01017-w.

Abstract

Thyroid cancer (TC) is a common endocrine malignancy with an increasing incidence worldwide. Early diagnosis is particularly important for TC patients, because it allows patients to receive treatment as early as possible. Artificial intelligence (AI) provides great advantages for complex healthcare systems by analyzing big data based on machine learning. Nowadays, AI is widely used in the early diagnosis of cancer such as TC. Ultrasound detection and fine needle aspiration biopsy are the main methods for early diagnosis of TC. AI has been widely used in the detection of malignancy in thyroid nodules by ultrasound images, cytopathology images and molecular markers. It shows great potential in auxiliary medical diagnosis. The latest clinical trial has shown that the performance of AI models matches with the diagnostic efficiency of experienced clinicians, and more efficient AI tools will be developed in the future. Therefore, in this review, we summarized the recent advances in the application of AI algorithms in assessing the risk of malignancy in thyroid nodules. The objective of this review was to provide a data base for the clinical use of AI-assisted diagnosis in TC, as well as to provide new ideas for the next generation of AI-assisted diagnosis in TC.

摘要

甲状腺癌(TC)是一种常见的内分泌恶性肿瘤,在全球范围内发病率呈上升趋势。早期诊断对TC患者尤为重要,因为这能让患者尽早接受治疗。人工智能(AI)通过基于机器学习分析大数据,为复杂的医疗系统带来了巨大优势。如今,AI广泛应用于诸如TC等癌症的早期诊断。超声检测和细针穿刺活检是TC早期诊断的主要方法。AI已广泛应用于通过超声图像、细胞病理学图像和分子标志物检测甲状腺结节中的恶性病变。它在辅助医学诊断方面显示出巨大潜力。最新的临床试验表明,AI模型的表现与经验丰富的临床医生的诊断效率相当,未来还将开发出更高效的AI工具。因此,在本综述中,我们总结了AI算法在评估甲状腺结节恶性风险应用方面的最新进展。本综述的目的是为AI辅助诊断在TC中的临床应用提供数据库,同时为下一代TC的AI辅助诊断提供新思路。

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