Enhancing infectious disease prediction model selection with multi-objective optimization: an empirical study.

As the pandemic continues to pose challenges to global public health, developing effective predictive models has become an urgent research topic. This study aims to explore the application of multi-objective optimization methods in selecting infectious disease prediction models and evaluate their impact on improving prediction accuracy, generalizability, and computational efficiency. In this study, the NSGA-II algorithm was used to compare models selected by multi-objective optimization with those selected by traditional single-objective optimization. The results indicate that decision tree (DT) and extreme gradient boosting regressor (XGBoost) models selected through multi-objective optimization methods outperform those selected by other methods in terms of accuracy, generalizability, and computational efficiency. Compared to the ridge regression model selected through single-objective optimization methods, the decision tree (DT) and XGBoost models demonstrate significantly lower root mean square error (RMSE) on real datasets. This finding highlights the potential advantages of multi-objective optimization in balancing multiple evaluation metrics. However, this study's limitations suggest future research directions, including algorithm improvements, expanded evaluation metrics, and the use of more diverse datasets. The conclusions of this study emphasize the theoretical and practical significance of multi-objective optimization methods in public health decision support systems, indicating their wide-ranging potential applications in selecting predictive models.