Suppr超能文献

急性疼痛管理中的新兴药物和策略:新型钠和钙通道阻滞剂、基于肽的药理药物以及非药物方法的作用不断演变。

Emerging Medications and Strategies in Acute Pain Management: Evolving Role of Novel Sodium and Calcium Channel Blockers, Peptide-Based Pharmacologic Drugs, and Non-Medicinal Methods.

机构信息

Department of Anesthesiology, Department of Pharmacology, Toxicology, and Neurosciences, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.

School of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.

出版信息

Curr Pain Headache Rep. 2024 Sep;28(9):853-862. doi: 10.1007/s11916-024-01265-z. Epub 2024 May 18.

Abstract

PURPOSE OF REVIEW

The present investigation evaluated integration of novel medication technology to enhance treatment options, while improving patient outcomes in acute pain management. In this regard, we focused on determining the role of development and utilization of cutting-edge pharmaceutical advancements, such as targeted drug delivery systems, as well as non-pharmacologic interventions in addressing acute pain states. Further research in this area is warranted related to the need for increased patient comfort and reduced adverse effects.

RECENT FINDINGS

Recent innovations and techniques are discussed including pharmacologic drugs targeting sodium and calcium channels, peptide-based pharmacologic drugs, and non-medicinal methods of alleviating pain such as soothing music or virtual reality. The present investigation included review of current literature on the application of these innovative technologies, analyzing mechanisms of action, pharmacokinetics, and clinical effectiveness. Our study also investigated the potential benefits in terms of pain relief, reduced side effects, and improved patient adherence. The research critically examines the challenges and considerations associated with implementing these technologies in acute pain management, considering factors like cost, accessibility, and regulatory aspects. Additionally, case studies and clinical trials are highlighted which demonstrate practical implications of these novel medication technologies in real-world scenarios. The findings aim to provide healthcare professionals with a comprehensive understanding of the evolving landscape in acute pain management while guiding future research and clinical practices toward optimizing their use in enhancing patient care.

摘要

目的综述

本研究评估了新型药物技术的整合,以增加治疗选择,同时改善急性疼痛管理的患者结局。在这方面,我们专注于确定开发和利用尖端药物进展(如靶向药物传递系统)以及非药物干预在解决急性疼痛状态中的作用。需要增加患者舒适度和减少不良反应,因此该领域需要进一步研究。

最近的发现

讨论了最近的创新和技术,包括针对钠和钙通道的药物、基于肽的药物以及减轻疼痛的非药物方法,如舒缓音乐或虚拟现实。本研究包括对这些创新技术应用的现有文献的回顾,分析作用机制、药代动力学和临床效果。我们的研究还研究了在急性疼痛管理中应用这些技术在减轻疼痛、减少副作用和提高患者依从性方面的潜在益处。研究批判性地审查了在急性疼痛管理中实施这些技术相关的挑战和考虑因素,考虑了成本、可及性和监管方面等因素。此外,还强调了案例研究和临床试验,这些研究展示了这些新型药物技术在实际情况下的实际意义。这些发现旨在为医疗保健专业人员提供急性疼痛管理中不断发展的领域的全面理解,并指导未来的研究和临床实践,以优化其在增强患者护理方面的应用。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验