Centro de Investigación para la Salud en América Latina (CISeAL), Pontificia Universidad Católica del Ecuador, Quito, Ecuador.
Institute of Collective Health (ISC), Federal University of Bahia, Bahia, Brazil.
Lancet Glob Health. 2024 Jun;12(6):e938-e946. doi: 10.1016/S2214-109X(24)00094-9.
Latin American and Caribbean countries are dealing with the combined challenges of pandemic-induced socicoeconomic stress and increasing public debt, potentially leading to reductions in welfare and health-care services, including primary care. We aimed to evaluate the impact of primary health-care coverage on child mortality in Latin America over the past two decades and to forecast the potential effects of primary health-care mitigation during the current economic crisis.
This multicountry study integrated retrospective impact evaluations in Brazil, Colombia, Ecuador, and Mexico from 2000 to 2019 with forecasting models covering up to 2030. We estimated the impact of coverage of primary health care on mortality rates in children younger than 5 years (hereafter referred to as under-5 mortality) across different age groups and causes of death, adjusting for all relevant demographic, socioeconomic, and health-care factors, with fixed-effects multivariable negative binomial models in 5647 municipalities with an adequate quality of vital statistics. We also performed several sensitivity and triangulation analyses. We integrated previous longitudinal datasets with validated dynamic microsimulation models and projected trends in under-5 mortality rates under alternative policy response scenarios until 2030.
High primary health-care coverage was associated with substantial reductions in post-neonatal mortality rates (rate ratio [RR] 0·72, 95% CI 0·71-0·74), toddler (ie, aged between 1 year and <5 years) mortality rates (0·75, 0·73-0·76), and under-5 mortality rates (0·81, 0·80-0·82), preventing 305 890 (95% CI 251 826-360 517) deaths of children younger than 5 years over the period 2000-19. High primary health-care coverage was also associated with lower under-5 mortality rates from nutritional deficiencies (RR 0·55, 95% CI 0·52-0·58), anaemia (0·64, 0·57-0·72), vaccine-preventable and vaccine-sensitive conditions (0·70, 0·68-0·72), and infectious gastroenteritis (0·78, 0·73-0·84). Considering a scenario of moderate economic crisis, a mitigation response strategy implemented in the period 2020-30 that increases primary health-care coverage could reduce the under-5 mortality rate by up to 23% (RR 0·77, 95% CI 0·72-0·84) when compared with a fiscal austerity response, and this strategy would avoid 142 285 (95% CI 120 217-164 378) child deaths by 2030 in Brazil, Colombia, Ecuador, and Mexico.
The improvement in primary health-care coverage in Brazil, Colombia, Ecuador, and Mexico over the past two decades has substantially contributed to improving child survival. Expansion of primary health-care coverage should be considered an effective strategy to mitigate the health effects of the current economic crisis and to achieve Sustainable Development Goals related to child health.
UK Medical Research Council.
For the Spanish and Portuguese translations of the abstract see Supplementary Materials section.
拉丁美洲和加勒比国家正面临着大流行病引起的社会经济压力和公共债务不断增加的双重挑战,这可能导致福利和医疗保健服务(包括初级保健)的减少。我们旨在评估过去二十年来拉丁美洲初级卫生保健覆盖率对儿童死亡率的影响,并预测当前经济危机期间初级卫生保健缓解措施的潜在影响。
本多国研究综合了巴西、哥伦比亚、厄瓜多尔和墨西哥 2000 年至 2019 年的回顾性影响评估,以及涵盖 2030 年的预测模型。我们通过固定效应多变量负二项式模型,在 5647 个具有足够生命统计质量的城市中,根据所有相关的人口、社会经济和医疗保健因素,对不同年龄组和死因的 5 岁以下儿童死亡率(以下简称 5 岁以下儿童死亡率)进行了覆盖范围对死亡率的影响进行了评估。我们还进行了几次敏感性和三角分析。我们将以前的纵向数据集与经过验证的动态微观模拟模型结合起来,并根据替代政策应对情景预测 2030 年 5 岁以下儿童死亡率的趋势。
高初级卫生保健覆盖率与新生儿后死亡率(比率[RR]0.72,95%CI0.71-0.74)、幼儿(即 1 岁至<5 岁)死亡率(RR0.75,0.73-0.76)和 5 岁以下儿童死亡率(RR0.81,0.80-0.82)的显著降低有关,在 2000-2019 年期间,预防了 305890(95%CI251826-360517)名 5 岁以下儿童的死亡。高初级卫生保健覆盖率也与营养缺乏(RR0.55,95%CI0.52-0.58)、贫血(RR0.64,95%CI0.57-0.72)、疫苗可预防和疫苗敏感疾病(RR0.70,0.68-0.72)和传染性肠胃炎(RR0.78,0.73-0.84)导致的 5 岁以下儿童死亡率降低有关。考虑到经济危机处于中等水平,2020-2030 年实施的缓解应对策略,如果与财政紧缩应对相比,增加初级卫生保健覆盖率,可能会使 5 岁以下儿童死亡率降低高达 23%(RR0.77,95%CI0.72-0.84),并将避免巴西、哥伦比亚、厄瓜多尔和墨西哥到 2030 年儿童死亡 142285(95%CI120217-164378)。
过去二十年来,巴西、哥伦比亚、厄瓜多尔和墨西哥初级卫生保健覆盖范围的改善极大地促进了儿童生存状况的改善。扩大初级卫生保健覆盖范围应被视为减轻当前经济危机对健康影响和实现与儿童健康有关的可持续发展目标的有效战略。
英国医学研究理事会。