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Cmmi-MHR 联合血栓弹力图参数对急性脑梗死的预测价值。

Predictive value of Cmmi-MHR combined with thromboelastography parameters in acute cerebral infarction.

机构信息

Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, Hubei, 430065, China.

General Medicine, Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, Hubei, 430065, China.

出版信息

BMC Med Imaging. 2024 May 18;24(1):115. doi: 10.1186/s12880-024-01299-0.

Abstract

Cerebral infarction is a common neurological disease with high rates of morbidity, mortality, and recurrence, posing a great threat to human life and health. Cerebral infarction is the second leading cause of death in the world and the leading cause of long-term disability in humans. The results of the third national retrospective sampling survey on causes of death in 2008 showed that cerebral infarction has become the leading cause of death in China and its mortality rate is 4-5 times that of European and American countries. Therefore, this article proposed a study on the predictive value of Cmmi-MHR combined with thromboelastography parameters that was performed for acute cerebral infarction. This paper mainly proposed a high frame rate imaging technology and analyzed its algorithm. In this article, in the experimental part, an in-depth analysis of the predictive value of the Monocyte-to-high-density lipoprotein cholesterol ratio (MHR) combined with thromboelastography parameters was performed for acute cerebral infarction. The final experimental results showed that HDL (OR = 1.695%, P-trend = 0.049) had a probability of death within 90 days of hospitalization (OR = 0.81, 95% CI = 1.06-3.11, P-trend = 0.523). There were no significant differences in mortality rate after 90 days. Regardless of adjusting for confounders such as age, gender, and NIHSS score, there was no significant difference in the risk of MHR or monocyte count within 90 days of hospitalization. The conclusion indicates that the combination of Cmmi-MHR and thromboelastography parameters provides a new perspective and method for the diagnosis and treatment of cerebral infarction, and provides important support for personalized treatment and management of cerebral infarction.

摘要

脑梗死是一种常见的神经系统疾病,发病率、死亡率和复发率均较高,严重威胁着人类的生命和健康。脑梗死是全球范围内仅次于心血管疾病的第二大致死原因,也是人类长期致残的首要原因。2008 年全国第三次死因回顾抽样调查结果显示,脑梗死已成为我国首位致死病因,其死亡率是欧美国家的 4-5 倍。因此,本文提出了一项关于 Cmmi-MHR 联合血栓弹力图参数对急性脑梗死预测价值的研究。本文主要提出了一种高帧率成像技术,并对其算法进行了分析。在本文中,在实验部分,深入分析了单核细胞-高密度脂蛋白胆固醇比值(MHR)联合血栓弹力图参数对急性脑梗死的预测价值。最终的实验结果表明,高密度脂蛋白(OR=1.695%,P-trend=0.049)与住院 90 天内死亡的概率相关(OR=0.81,95%CI=1.06-3.11,P-trend=0.523)。90 天后死亡率无显著差异。无论是否调整年龄、性别和 NIHSS 评分等混杂因素,住院 90 天内 MHR 或单核细胞计数的死亡风险均无显著差异。结论表明,Cmmi-MHR 与血栓弹力图参数的联合为脑梗死的诊断和治疗提供了新的视角和方法,为脑梗死的个体化治疗和管理提供了重要支持。

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