Department of Dermatology, University of California Davis Health, Sacramento, California, USA Touro University California College of Osteopathic Medicine, Vallejo, California, USA.
Dermatol Online J. 2024 Mar 15;30(1). doi: 10.5070/D330163280.
Herpetic geometric glossitis is a unique morphologic variant of HSV (herpes simplex virus) type 1 infection on the dorsum of the tongue that presents as an extremely painful linear central lingual fissure with a branched pattern. in the center of the tongue; there is a branched pattern of fissures that extend bilaterally from the central linear fissure. Herpetic geometric glossitis has been reported in 11 patients; 8 of these individuals were immunocompromised. Medical conditions and immunosuppressive medication treatment (7 patients) or only medical disorders (3 patients) or neither (1 patient) were present. HSV type 1 infection was diagnosed by viral culture in (7 patients), Tzanck preparation (2 patients) or clinically (2 patients). Mucocutaneous HSV infection at non-lingual locations--including the lips, labial mucosa, face and chest--were observed in 5 patients. All patients' symptoms and lesions responded to treatment with oral antiviral therapy: acyclovir (9 patients), famciclovir (1 patient) or valacyclovir (1 patient). The lingual pain and dorsal tongue fissures completely resolved completely within two to 14 days. In summary, herpetic geometric glossitis is a unique HSV type 1 infection, usually in immunocompromised patients, that occurs on the dorsal tongue and responds completely after treatment with orally administered antiviral therapy.
疱疹性几何舌炎是一种独特的形态学变异型单纯疱疹病毒（HSV）1 型感染，发生于舌背，表现为极度疼痛的线性中央舌裂，呈分支状。在舌的中心；有分支状的裂缝，从中央线性裂缝向两侧延伸。疱疹性几何舌炎已在 11 例患者中报告；其中 8 例为免疫功能低下者。存在医疗条件和免疫抑制药物治疗（7 例）或仅存在医疗疾病（3 例）或两者均不存在（1 例）。HSV 1 型感染通过病毒培养（7 例）、Tzanck 准备（2 例）或临床诊断（2 例）确诊。5 例患者观察到非舌部的黏膜皮肤 HSV 感染，包括唇、唇黏膜、面部和胸部。所有患者的症状和病变均对口服抗病毒治疗有效：阿昔洛韦（9 例）、泛昔洛韦（1 例）或伐昔洛韦（1 例）。舌痛和舌背裂在 2 至 14 天内完全缓解。总之，疱疹性几何舌炎是一种独特的单纯疱疹病毒 1 型感染，通常发生在免疫功能低下的患者中，发生于舌背，经口服抗病毒治疗后完全缓解。
