Suppr超能文献

临床侵袭性坏死性化脓性肉芽肿性皮炎的混杂病例。

A confounding clinically aggressive case of necrotizing granulomatous and suppurative dermatitis.

机构信息

Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, Utah, USA.

出版信息

Dermatol Online J. 2024 Mar 15;30(1). doi: 10.5070/D330163283.

Abstract

Superficial granulomatous pyoderma gangrenosum is a rare, superficial, vegetating form of pyoderma gangrenosum that tends to occur as a single lesion, most commonly on the trunk. Herein, we report a clinically confounding case of disseminated superficial granulomatous pyoderma gangrenosum in a patient with a 5-year history of painful and chronic ulcerations of the bilateral upper extremities and face in a sun exposed distribution. This was a diagnostically challenging case due to the treatment-refractory nature of our patient's skin lesions and the atypical clinical and histologic presentations encountered. We review our clinical decision process and acknowledge other entities that were considered during the clinical course of this case. Additionally, we discuss the lack of responsiveness to various treatment options with eventual successful clearance of this patient's active skin disease with initiation of adalimumab.

摘要

浅表性化脓性坏疽性脓皮病是一种罕见的、浅表性、有植被的坏疽性脓皮病,通常表现为单个病变,最常见于躯干。在此,我们报告了一例临床上令人困惑的弥漫性浅表化脓性坏疽性脓皮病病例,患者 5 年来双侧上肢和面部暴露于阳光下的部位出现疼痛性慢性溃疡。由于患者皮肤病变的难治性和遇到的非典型临床和组织学表现,这是一个具有诊断挑战性的病例。我们回顾了我们的临床决策过程,并承认在该病例的临床过程中考虑了其他实体。此外,我们还讨论了对各种治疗方案的反应不佳,最终通过开始使用阿达木单抗成功清除了该患者的活动性皮肤病。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验