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酒精性肝硬化中肝上皮样血管平滑肌脂肪瘤的临床回顾与文献分析:一例报告

Clinical review and literature analysis of hepatic epithelioid angiomyolipoma in alcoholic cirrhosis: A case report.

作者信息

Guo Jing-Qiang, Zhou Jia-Hui, Zhang Kun, Lv Xin-Liang, Tu Chao-Yong

机构信息

Department of Hepatobiliary and Pancreatic Surgery, Lishui Municipal Central Hospital, Lishui 323000, Zhejiang Province, China.

Department of Pathology, Lishui Municipal Central Hospital, Lishui 323000, Zhejiang Province, China.

出版信息

World J Clin Cases. 2024 May 16;12(14):2382-2388. doi: 10.12998/wjcc.v12.i14.2382.

DOI:10.12998/wjcc.v12.i14.2382
PMID:38765741
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11099400/
Abstract

BACKGROUND

Hepatic epithelioid angiomyolipoma (HEA) has a low incidence and both clinical manifestations and imaging lack specificity. Thus, it is easy to misdiagnose HEA as other tumors of the liver, especially in the presence of liver diseases such as hepatitis cirrhosis. This article reviewed the diagnosis and treatment of a patient with HEA and alcoholic cirrhosis, and analyzed the literature, in order to improve the understanding of this disease.

CASE SUMMARY

A 67-year-old male patient with a history of alcoholic cirrhosis was admitted due to the discovery of a space-occupying lesion in the liver. Based on the patient's history, laboratory examinations, and imaging examinations, a malignant liver tumor was considered and laparoscopic partial hepatectomy was performed. Postoperative pathology showed HEA. During outpatient follow-up, the patient showed no sign of recurrence.

CONCLUSION

HEA is difficult to make a definite diagnosis before surgery. HEA has the potential for malignant degeneration. If conditions permit, surgical treatment is recommended.

摘要

背景

肝上皮样血管平滑肌脂肪瘤(HEA)发病率较低,其临床表现及影像学表现均缺乏特异性。因此,HEA容易被误诊为肝脏的其他肿瘤,尤其是在存在如肝炎肝硬化等肝脏疾病的情况下。本文回顾了1例HEA合并酒精性肝硬化患者的诊治过程,并进行文献分析,以提高对该病的认识。

病例摘要

1例67岁男性患者,有酒精性肝硬化病史,因肝脏发现占位性病变入院。根据患者病史、实验室检查及影像学检查,考虑为肝脏恶性肿瘤,行腹腔镜下肝部分切除术。术后病理显示为HEA。门诊随访期间,患者无复发迹象。

结论

HEA术前难以明确诊断。HEA有恶变潜能。若条件允许,建议手术治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87a9/11099400/f6b015ba3276/WJCC-12-2382-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87a9/11099400/6386c071a3ee/WJCC-12-2382-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87a9/11099400/290b57708579/WJCC-12-2382-g003.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87a9/11099400/f6b015ba3276/WJCC-12-2382-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87a9/11099400/6386c071a3ee/WJCC-12-2382-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87a9/11099400/c6ab0448cc42/WJCC-12-2382-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87a9/11099400/290b57708579/WJCC-12-2382-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87a9/11099400/b4a836b4787d/WJCC-12-2382-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87a9/11099400/f6b015ba3276/WJCC-12-2382-g005.jpg

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本文引用的文献

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Hell J Nucl Med. 2022 May-Aug;25(2):205-209. doi: 10.1967/s002449912480. Epub 2022 Aug 3.
2
Two case reports and literature review for hepatic epithelioid angiomyolipoma: Pitfall of misdiagnosis.肝上皮样血管平滑肌脂肪瘤的两例病例报告及文献复习:误诊陷阱
World J Clin Cases. 2019 Apr 26;7(8):972-983. doi: 10.12998/wjcc.v7.i8.972.
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Comparison of MRI Features of Epithelioid Hepatic Angiomyolipoma and Hepatocellular Carcinoma: Imaging Data From Two Centers.
上皮样肝血管平滑肌脂肪瘤与肝细胞癌的MRI特征比较:来自两个中心的影像数据
Front Oncol. 2018 Dec 12;8:600. doi: 10.3389/fonc.2018.00600. eCollection 2018.
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Fatty Liver Disease and Hepatocellular Carcinoma: The Pathologist's View.脂肪性肝病与肝细胞癌:病理医师的视角。
Adv Exp Med Biol. 2018;1032:55-69. doi: 10.1007/978-3-319-98788-0_4.
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Primary perivascular epithelioid cell tumors of the liver: CT/MRI findings and clinical outcomes.肝脏原发性血管周上皮样细胞瘤:CT/MRI 表现与临床结局。
Abdom Radiol (NY). 2017 Jun;42(6):1705-1712. doi: 10.1007/s00261-017-1074-y.
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Clinico-pathological correlation of hepatic angiomyolipoma: a series of 23 resection cases.肝血管平滑肌脂肪瘤的临床病理相关性:23例切除病例系列研究
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