Liu Wentao, Meng Zihui, Liu Hongyu, Li Wei, Wu Qiong, Zhang Xuewen, E Changyong
Department of Hepatobiliary and Pancreatic Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin 130033, P.R. China.
Department of Pathology, China-Japan Union Hospital of Jilin University, Changchun, Jilin 130033, P.R. China.
Oncol Lett. 2016 Jun;11(6):3669-3675. doi: 10.3892/ol.2016.4443. Epub 2016 Apr 15.
Hepatic epithelioid angiomyolipoma (EAML) is a rare type of hepatic tumor. Due to a lack of adequate understanding about this tumor, hepatic EAML is often misdiagnosed as other diseases with similar clinical characteristics such as hepatic cancer. In the present study, 3 cases of hepatic EAML are reported, and the main clinicopathological features of this disease are presented, based on a literature search that included articles published in English between February 2000 and September 2014. A total of 24 hepatic EAML cases were considered, of which, 17 were females and 4 presented multiple liver lesions. Among the patients with single lesions, 2 underwent surgery and relapsed after 5 months and 9 years, respectively. Immunohistochemical staining was positive for human melanoma black-45 in the present 3 cases. The aim of the present study was to focus the attention of clinicians on this type of hepatic tumor in order to improve its diagnosis and treatment.
肝上皮样血管平滑肌脂肪瘤（EAML）是一种罕见的肝脏肿瘤。由于对这种肿瘤缺乏足够的了解，肝EAML常被误诊为具有相似临床特征的其他疾病，如肝癌。在本研究中，报告了3例肝EAML病例，并根据对2000年2月至2014年9月间发表的英文文章的文献检索，介绍了该疾病的主要临床病理特征。共纳入24例肝EAML病例，其中女性17例，4例出现多发肝脏病变。在单发病变的患者中，2例接受了手术，分别在5个月和9年后复发。本研究中的3例病例免疫组织化学染色显示人黑素瘤黑色素-45呈阳性。本研究的目的是引起临床医生对这种肝脏肿瘤的关注，以改善其诊断和治疗。
