[Intrahypothalamic connections of the lateral hypothalamus].

Using the axon degeneration method by R. Fink and L. Heimer, organization of intrathalamic connections between various areas of the lateral hypothalamus have been studied after unisided electrolitic lesion. At any location of the injury foci, similar patterns are observed in ipsilateral distribution of degenerating fibers along the whole lateral preoptico-hypothalamic area. The most massive degeneration is observed in the zone where the medial forebrain bundle (MFB) fibers run. The degenerating fibers spread forward--into the septal area, and backward--into the mesencephalic part of the brain. The rostral and caudal parts of the lateral hypothalamus, taking part in formation of the MFB collateralies towards the thalamus, are connected with various thalamic nuclei. Massive preterminal degeneration in the perifornical zone and single argerophile granules in the medial hypothalamus convincingly demonstrate an important role of the intermediate zone for connections of its medial and lateral parts with each other. The conclusion that the intrahypothalamic connections of the lateral hypothalamus are realized within the MFB system supports the modern notion on a close connection of the lateral hypothalamus with the system of longitudinal diffuse bundles of fibers of the medial anterocerebral pathway that run through it.