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与梗阻性脑积水相关的运动不能性缄默症和帕金森综合征。

Akinetic mutism and parkinsonism associated with obstructive hydrocephalus.

作者信息

Berger L, Gauthier S, Leblanc R

出版信息

Can J Neurol Sci. 1985 Aug;12(3):255-8. doi: 10.1017/s0317167100047119.

Abstract

We report the case of a patient with idiopathic aqueductal stenosis and hydrocephalus who had several episodes of akinetic mutism, each preceded by shunt malfunction, that resolved with shunt revision. She also developed a parkinson's syndrome resistant to shunt revision but responsive to antiparkinsonian medications. The parkinson's syndrome and the episodes of akinetic mutism may be related to a reduction of dopaminergic input to the striatum and to the cingulate and frontal cortex brought about or worsened by ventricular dilatation.

摘要

我们报告了一例患有特发性导水管狭窄和脑积水的患者,该患者出现了数次运动不能性缄默发作,每次发作前均有分流管故障,经分流管修复后症状缓解。她还出现了对分流管修复有抵抗但对抗帕金森药物有反应的帕金森综合征。帕金森综合征和运动不能性缄默发作可能与脑室扩张导致或加重的纹状体、扣带回和额叶皮质多巴胺能输入减少有关。

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