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慢性心力衰竭的长期左心室辅助装置治疗的经济学方面。

Economic aspects of long-term left ventricular assist device treatment for chronic heart failure.

机构信息

Department of Cardiothoracic Surgery, University Hospital of Muenster, Albert Schweitzer Campus 1, A1, 48149, Muenster, Germany.

Interdisciplinary Heart Failure Section, University Hospital of Muenster, Muenster, Germany.

出版信息

ESC Heart Fail. 2024 Oct;11(5):2849-2856. doi: 10.1002/ehf2.14774. Epub 2024 May 20.

Abstract

AIMS

Technological advances and the current shortage of donor organs have contributed to an increase in the number of left ventricular assist device (LVAD) implantations in patients with end-stage heart failure. Demographic change and medical progress might raise the number of these patients, resulting in a further increase in the number of LVAD implantations. The aim of this study was to evaluate the long-term costs of LVAD therapy and identify diagnoses resulting in expensive stays.

METHODS AND RESULTS

In this retrospective analysis of prospectively collected data, all patients after implantation of a second- or third-generation LVAD by 31 March 2022 were included. In addition to demographic and survival data, revenues and case mix points were determined for each patient. Of the 163 patients included, 75.5% were male. The mean age at LVAD implantation was 52 ± 14 years. The mean survival was 1458 ± 127 days. During follow-up, the total inpatient treatment time per patient was 70 ± 87 days. The average duration of outpatient treatment was 55.1%, based on the total duration of support. The average revenue per patient for the implant stay was $193 192.35 ± $111 801.29, for inpatient readmissions $52 068.96 ± $116 630.00, and for outpatient care $53 195.94 ± $62 363.53.

CONCLUSIONS

LVAD implantation in patients with end-stage heart failure leads to improved survival but a significant increase in treatment costs. Further multi-centre studies are necessary in order to be able to assess the effects of long-term LVAD treatment on the healthcare system.

摘要

目的

技术进步和当前供体器官短缺导致终末期心力衰竭患者中左心室辅助装置(LVAD)植入数量增加。人口结构变化和医疗进步可能会增加这些患者的数量,从而进一步增加 LVAD 植入数量。本研究旨在评估 LVAD 治疗的长期成本,并确定导致昂贵住院费用的诊断。

方法和结果

在这项前瞻性收集数据的回顾性分析中,纳入了截至 2022 年 3 月 31 日接受第二代或第三代 LVAD 植入的所有患者。除了人口统计学和生存数据外,还确定了每位患者的收入和病例组合点数。在纳入的 163 名患者中,75.5%为男性。LVAD 植入时的平均年龄为 52±14 岁。平均生存时间为 1458±127 天。在随访期间,每位患者的总住院治疗时间为 70±87 天。基于支持的总持续时间,门诊治疗的平均持续时间为 55.1%。每位患者的植入住院治疗收入为 193192.35 美元±111801.29 美元,住院再入院收入为 52068.96 美元±116630.00 美元,门诊护理收入为 53195.94 美元±62363.53 美元。

结论

LVAD 植入治疗终末期心力衰竭患者可提高生存率,但治疗费用显著增加。需要进一步的多中心研究,以便能够评估长期 LVAD 治疗对医疗保健系统的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81a0/11424323/4daed9fd2511/EHF2-11-2849-g003.jpg

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