Burgell Rebecca Elizabeth, Hoey Louisa, Norton Kate, Fitzpatrick Jessica
Gastroenterologist Functional GI Disorders Service Alfred Health and Monash University Melbourne Australia.
Clinical Psychologist Functional GI Disorders service, Alfred Health Melbourne Australia.
JGH Open. 2024 May 20;8(5):e13072. doi: 10.1002/jgh3.13072. eCollection 2024 May.
Disorders of brain-gut interaction (DGBI) are highly prevalent in our community with a negative burden on the quality of life and function. Symptoms are frequently food-induced, and psychological disorders are commonly co-morbid and contribute greatly to symptom severity and healthcare utilization, which can complicate management. Pathophysiological contributors to the development and maintenance of DGBI are best appreciated within the biopsychosocial model of illness. Established treatments include medical therapies targeting gastrointestinal physiology, luminal microbiota or visceral sensitivity, dietary treatments including dietary optimization and specific therapeutic diets such as a low-FODMAP diet, and psychological interventions. The traditional "medical model" of care, driven predominantly by doctors, poorly serves sufferers of DBGI, with research indicating that a multidisciplinary, integrated-care approach produces better outcomes. This narrative review explores the current evidence for multidisciplinary care and provides the best practice recommendations for physicians and healthcare systems managing such patients.
脑-肠互动障碍(DGBI)在我们的社区中极为普遍,对生活质量和功能产生负面影响。症状通常由食物诱发,心理障碍常与之并存,且对症状严重程度和医疗保健利用有很大影响,这会使管理变得复杂。在生物心理社会疾病模型中,最能理解导致DGBI发生和维持的病理生理因素。既定的治疗方法包括针对胃肠生理、肠道微生物群或内脏敏感性的药物治疗、饮食治疗,包括饮食优化和特定的治疗性饮食,如低发酵碳水化合物饮食,以及心理干预。主要由医生主导的传统“医疗模式”对DGBI患者的治疗效果不佳,研究表明多学科综合护理方法能产生更好的结果。这篇叙述性综述探讨了多学科护理的现有证据,并为管理此类患者的医生和医疗系统提供了最佳实践建议。