Nagaja Sharanika A, John Rubin S, Kumar Santhosh P, Krishnan Murugesan
Oral and Maxillofacial Surgery, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Cureus. 2024 Apr 17;16(4):e58498. doi: 10.7759/cureus.58498. eCollection 2024 Apr.
Introduction Mesotherapy is a wide range of minimally invasive injections. In mesotherapy, a mixture of various tonics is injected into the skin. These include plant extracts, various medications, vitamins, enzymes, hormones, growth factors, and other factors that will help treat alopecia. Most commonly, a mixture of platelet-rich plasma (PRP) and vitamins is used. In mesotherapy treatment for hair regrowth in the temporal region, zygomaticotemporal nerve blocks, supratrochlear nerve blocks, and supraorbital nerve blocks are given. The zygomaticotemporal nerve, supraorbital nerve, and supratrochlear nerve are the branches of the trigeminal nerve. They provide sensation on the lateral side of the forehead, which is the temple region. Methods A sample size of 100 people was taken for the study who were undergoing mesotherapy in the bilateral temporal region for alopecia. Each group had 50 subjects: group I was given supratrochlear, supraorbital, and zygomaticotemporal nerve blocks as local anesthesia techniques, and group II was given supratrochlear and supraorbital nerve blocks. PRP was injected using an insulin syringe. Pain was assessed using a visual analog scale (VAS). Results During the procedure, a mean VAS of 1 and 3 was observed in groups I and II, respectively, during the procedure (p-value 0.023). A mean VAS of 3 and 5 was observed in groups I and II, respectively, after three hours (p-value 0.000). This shows a significant difference in the pain experienced by the subjects between the groups. Conclusion This study proves that the zygomaticotemporal nerve, used along with supratrochlear and supraorbital nerve blocks, is better at producing analgesia and reducing pain.
引言
中胚层疗法是一系列微创注射疗法。在中胚层疗法中，将各种滋补剂的混合物注入皮肤。这些包括植物提取物、各种药物、维生素、酶、激素、生长因子以及其他有助于治疗脱发的因子。最常用的是富含血小板血浆（PRP）和维生素的混合物。在颞部区域进行促进头发生长的中胚层疗法时，会进行颧颞神经阻滞、滑车上神经阻滞和眶上神经阻滞。颧颞神经、眶上神经和滑车上神经是三叉神经的分支。它们在前额外侧（即颞部区域）提供感觉。
方法
选取100名在双侧颞部区域接受中胚层疗法治疗脱发的患者作为研究样本。每组有50名受试者：第一组采用滑车上、眶上和颧颞神经阻滞作为局部麻醉技术，第二组采用滑车上和眶上神经阻滞。使用胰岛素注射器注射PRP。采用视觉模拟评分法（VAS）评估疼痛程度。
结果
在操作过程中，第一组和第二组的平均VAS分别为1和3（p值为0.023）。三小时后，第一组和第二组的平均VAS分别为3和5（p值为0.000）。这表明两组受试者所经历的疼痛存在显著差异。
结论
本研究证明，颧颞神经与滑车上神经和眶上神经阻滞联合使用时，在产生镇痛效果和减轻疼痛方面效果更佳。
