Kotovskaia A R, Krasnov I B, Shipov A A
Kosm Biol Aviakosm Med. 1985 Jul-Aug;19(4):53-7.
Rats housed as a group per cage were centrifuged for 21 and 30 days at 1.1 and 2.0 G. The following parameters were measured: motor activity, body mass, static and dynamic endurance, acceleration (+Gz) tolerance, vestibular function, equilibrium function, skeletal muscle contractility, bone dynamics, gas exchange, blood biochemistry; weight of adrenals, thymus and thyroid gland; morphology of adrenals, thyroid gland, and cortex of the cerebellum nodulus; biochemistry of blood hormones, energy metabolism enzymes in the liver, bone phosphatases, myosin Ca-Mg-ATPase in the myocardium, protein sulfhydryl groups in the cerebellar motor cortex. The study has demonstrated that prolonged (1/50 of their life time) centrifugation of unrestrained rats causes no deterioration of many physiological functions, i.e., rotation produces no adverse effects on the animal body.
将每组大鼠置于一个笼子中，分别在1.1G和2.0G的条件下进行21天和30天的离心处理。测量了以下参数：运动活动、体重、静态和动态耐力、加速度（+Gz）耐受性、前庭功能、平衡功能、骨骼肌收缩力、骨动力学、气体交换、血液生化指标；肾上腺、胸腺和甲状腺的重量；肾上腺、甲状腺和小脑蚓部皮质的形态；血液激素生化指标、肝脏中的能量代谢酶、骨磷酸酶、心肌中的肌球蛋白钙-镁-ATP酶、小脑运动皮质中的蛋白质巯基。该研究表明，对未受约束的大鼠进行长时间（其寿命的1/50）离心处理不会导致许多生理功能恶化，即旋转对动物身体没有不良影响。
