McCollum J S, Dundee J W, Halliday N J, Clarke R S
Postgrad Med J. 1985;61 Suppl 3:85-7.
In younger patients, 2.25 mg/kg is a reliable induction dose of propofol, whereas this level falls to 1.5 mg/kg in older patients. The incidence of hypotension and apnoea is dose-dependent in all patients.