Cinti S, Balercia G, Osculati F, Dantchev D, Mathé G
Biomed Pharmacother. 1985;39(3):123-34.
In this report the authors show the main ultrastructural features of malignant non-Hodgkin's lymphomas and lymphoid leukemias, trying to outline the more important findings useful to diagnostic purpose. Since, from an immunologic point of view, lymphoid malignancies reflect the main steps of normal B and T ontogenesis, the various tumours are progressively presented in relation to their stage of phenotypic differentiation. An exact knowledge of the potential information from electron microscopy and its intrinsic limitations, including the high cost and the time expense, permit a correct use of this investigation in diagnostic procedure in lymphoid malignancies.
在本报告中，作者展示了恶性非霍奇金淋巴瘤和淋巴样白血病的主要超微结构特征，试图概述对诊断有重要意义的更重要发现。从免疫学角度来看，淋巴样恶性肿瘤反映了正常B细胞和T细胞发生的主要阶段，因此，各种肿瘤根据其表型分化阶段逐步呈现。准确了解电子显微镜的潜在信息及其固有局限性，包括高成本和耗时，有助于在淋巴样恶性肿瘤的诊断过程中正确使用这项检查。
