Hamburg A, Brynes R K, Reese C, Golomb H M
Lab Invest. 1976 Feb;34(2):207-15.
The ultrastructural and surface marker characteristics of human cord blood lymphocytes were studied. These properties were compared with those in cells of patients in the leukemic phase of both malignant lymphoma, poorly differentiated lymphocytic type, and mycosis fungoides. Nuclear folding in cord blood lymphocytes was similar to that seen in lymphocytes of patients with malignant lymphoma, poorly differentiated lymphocytic type and mycosis fungoides. Surface marker characteristics of cord blood lymphocytes included increased percentages of surface IgD on cells bearing surface immunoglobulins and decreased percentages of E-rosette-forming cells. The hypothesis that both malignant lymphoma, poorly differentiated lymphocytic type and mycosis fungoides represent an arrest in the normal lymphocyte maturation sequence is discussed.
对人脐带血淋巴细胞的超微结构和表面标志物特征进行了研究。将这些特性与恶性淋巴瘤（低分化淋巴细胞型）和蕈样肉芽肿白血病期患者细胞的特性进行了比较。脐带血淋巴细胞的核折叠与低分化淋巴细胞型恶性淋巴瘤和蕈样肉芽肿患者淋巴细胞中的核折叠相似。脐带血淋巴细胞的表面标志物特征包括：带有表面免疫球蛋白的细胞上表面IgD百分比增加，以及E花环形成细胞百分比降低。文中讨论了低分化淋巴细胞型恶性淋巴瘤和蕈样肉芽肿均代表正常淋巴细胞成熟序列停滞的假说。
