Duke University, Durham, NC, United States of America.
Duke University Medical Center, Durham, NC, United States of America.
PLoS One. 2024 May 22;19(5):e0301105. doi: 10.1371/journal.pone.0301105. eCollection 2024.
Misophonia is a condition characterized by negative affect, intolerance, and functional impairment in response to particular repetitive sounds usually made by others (e.g., chewing, sniffing, pen tapping) and associated stimuli. To date, researchers have largely studied misophonia using self-report measures. As the field is quickly expanding, assessment approaches need to advance to include more objective measures capable of differentiating those with and without misophonia. Although several studies have used sounds as experimental stimuli, few have used standardized stimuli sets with demonstrated reliability or validity. To conduct rigorous research in an effort to better understand misophonia, it is important to have an easily accessible, standardized set of acoustic stimuli for use across studies. Accordingly, in the present study, the International Affective Digitized Sounds (IADS-2), developed by Bradley and Lang (Bradley MM et al., 2007), were used to determine whether participants with misophonia responded to certain standardized sounds differently than a control group. Participants were 377 adults (132 participants with misophonia and 245 controls) recruited from an online platform to complete several questionnaires and respond to four probes (arousal, valence, similarity to personally-relevant aversive sounds, and sound avoidance) in response to normed pleasant, unpleasant, and neutral IADS-2 sounds. Findings indicated that compared to controls, participants with high misophonia symptoms rated pleasant and neutral sounds as significantly more (a) arousing and similar to trigger sounds in their everyday life, (b) unpleasant and (c) likely to be avoided in everyday life. For future scientific and clinical innovation, we include a ranked list of IADS-2 stimuli differentiating responses in those with and without misophonia, which we call the IADS-M.
恐音症是一种以对特定重复声音（例如咀嚼、嗅探、笔尖敲击声）和相关刺激产生的负面情绪、无法容忍和功能障碍为特征的病症。迄今为止，研究人员主要使用自我报告的测量方法来研究恐音症。随着该领域的迅速发展，评估方法需要改进，以包括更能区分有和没有恐音症的人更客观的测量方法。尽管有几项研究使用声音作为实验刺激，但很少有研究使用具有可靠性或有效性的标准化刺激集。为了开展严谨的研究，努力更好地理解恐音症，拥有一套易于获取、标准化的声学刺激集对于跨研究使用非常重要。因此，在本研究中，使用了由 Bradley 和 Lang 开发的国际情感数字化声音（IADS-2）（Bradley MM 等人，2007 年），以确定患有恐音症的参与者是否对某些标准化声音的反应与对照组不同。参与者为 377 名成年人（132 名患有恐音症的参与者和 245 名对照组），他们从一个在线平台招募，以完成几个问卷，并对四个探针（唤醒度、效价、与个人相关的厌恶声音的相似性以及声音回避）做出反应，以响应规范的愉快、不愉快和中性 IADS-2 声音。研究结果表明，与对照组相比，高恐音症症状参与者将愉快和中性声音评定为明显（a）更唤醒和类似于日常生活中的触发声音，（b）更不愉快，以及（c）更有可能在日常生活中回避。为了未来的科学和临床创新，我们包括了一个 IADS-2 刺激的排序列表，区分了有和没有恐音症的人的反应，我们称之为 IADS-M。
