Barolet Augustin C, Barolet Daniel
Department of Surgery, Regenerative Medicine Division, CHU de Quebec-Université Laval Research Centre, Quebec City, Quebec, Canada.
RoseLab Skin Optics Research Laboratory, Laval, Quebec, Canada.
Photobiomodul Photomed Laser Surg. 2024 May;42(5):339-342. doi: 10.1089/photob.2023.0184.
This study aimed to investigate the effectiveness of prophylactic photobiomodulation (PBM) in reducing postinflammatory hyperpigmentation (PIH) induced by carbon dioxide (CO) laser resurfacing in a patient with periorbital syringomas. PIH is a common condition characterized by abnormal skin pigmentation after an inflammatory process occurring in up to 20-30% of patients undergoing CO laser resurfacing. The patient was treated with PBM using a pulsed home-use device at 630 nm before and after CO laser treatment. The patient was asked to treat the right periorbital area before and after the CO laser treatment, which was continued once a day for 2 consecutive weeks. At 12 weeks, PIH was significantly reduced on the treated side compared with the contralateral untreated side (leading to persistent erythema at 6 months). This is the first report of prophylactic treatment of CO laser-induced dyschromia using PBM.
本研究旨在探讨预防性光生物调节（PBM）在减少一名患有眶周汗管瘤的患者因二氧化碳（CO）激光换肤引起的炎症后色素沉着（PIH）方面的有效性。PIH是一种常见病症，其特征是在接受CO激光换肤的患者中，高达20%-30%的人在炎症过程后出现皮肤色素沉着异常。该患者在CO激光治疗前后使用波长为630nm的家用脉冲设备进行PBM治疗。要求患者在CO激光治疗前后对右侧眶周区域进行治疗，连续2周每天进行一次。在12周时，与对侧未治疗侧相比，治疗侧的PIH明显减轻（导致6个月时持续红斑）。这是关于使用PBM预防性治疗CO激光引起的色素异常的首次报告。
