Sekizuka H, Noro K, Haruyama S, Kiribuchi Y, Hayashi F
Gan No Rinsho. 1985 Sep;31(11):1381-6.
The cell-mediated immunity of gastric cancer subjects was investigated during the postoperative follow-up period from three to 12 months after surgery. The lymphocyte blastogenesis, the T cell count, the lymphocyte count and the lymphocyte percentage were significantly decreased in groups of experimental laparotomy and noncurative gastrectomy, compared with that of nonrecurrent cases after curative gastrectomy. The effects of the administration of immunopotentiators, the streptococcal preparation OK-432, and the protein-bound polysaccharide PSK, were studied in groups of curative gastrectomy. The lymphocyte blastogenesis, the T cell count and the lymphocyte count were slightly elevated in the OK-432 group.
在胃癌患者术后3至12个月的随访期内，对其细胞介导免疫进行了研究。与根治性胃切除术后无复发的病例相比，实验性剖腹术组和非根治性胃切除术组的淋巴细胞增殖、T细胞计数、淋巴细胞计数和淋巴细胞百分比均显著降低。在根治性胃切除术组中，研究了免疫增强剂、链球菌制剂OK-432和蛋白结合多糖PSK的给药效果。OK-432组的淋巴细胞增殖、T细胞计数和淋巴细胞计数略有升高。
