Department of Chemistry, University of Ghana, Accra, Ghana.
Department of Food Processing Engineering, University of Ghana, Accra, Ghana.
Food Addit Contam Part B Surveill. 2024 Sep;17(3):213-222. doi: 10.1080/19393210.2024.2351575. Epub 2024 May 22.
This study presents the results of aflatoxin contamination of maize and groundnuts in major markets in Accra and assesses the population's exposure to aflatoxins. Raw maize and groundnuts from 6 major markets in Accra were sampled and analysed for their aflatoxin content. A total of 92 samples comprising 48 maize and 44 groundnuts were analysed using high-performance liquid chromatography, after extraction with methanol/water and cleanup on an immunoaffinity column. Total aflatoxins were quantified in 98% of the maize samples and 70% of the groundnut samples, with concentrations ranging from 0.60 to 1065 µg/kg and 0.20 to 627 µg/kg, respectively. Exposure assessment showed an estimated daily intake of 0.436 μg/kg bw/day and 0.0632 μg/kg bw/day for maize and groundnut consumption, respectively, suggesting significant health risks for consumers. The high prevalence and concentrations of aflatoxins call for an urgent need for measures to control exposure of the Ghanaian population.
本研究报告了加纳主要市场中玉米和花生的黄曲霉毒素污染情况,并评估了人群对黄曲霉毒素的暴露情况。从阿克拉的 6 个主要市场中采集了生玉米和花生样本,并对其黄曲霉毒素含量进行了分析。总共分析了 92 个样本,其中包括 48 个玉米样本和 44 个花生样本,使用高效液相色谱法,在甲醇/水提取和免疫亲和柱净化后进行分析。在 98%的玉米样本和 70%的花生样本中检测到总黄曲霉毒素,浓度范围分别为 0.60 至 1065μg/kg 和 0.20 至 627μg/kg。暴露评估显示,玉米和花生消费的每日摄入量估计分别为 0.436μg/kg bw/day 和 0.0632μg/kg bw/day,这对消费者构成了重大健康风险。黄曲霉毒素的高流行率和浓度需要采取紧急措施来控制加纳人口的暴露。