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结核性胸膜炎治疗开始后发生的免疫球蛋白A血管炎:一例报告及文献复习

Immunoglobulin A Vasculitis After Initiation of Treatment for Tuberculous Pleurisy: A Case Report and Literature Review.

作者信息

Hiramatsu Yuri, Tobino Kazunori, Saito Yukari, Sogabe Shota, Murakami Yosuke

机构信息

Respiratory Medicine, Iizuka Hospital, Fukuoka, JPN.

出版信息

Cureus. 2024 Apr 22;16(4):e58707. doi: 10.7759/cureus.58707. eCollection 2024 Apr.

Abstract

Immunoglobulin A vasculitis (IgAV), also known as Henoch-Schönlein purpura (HSP), is a disease that causes inflammation and bleeding in small blood vessels in the skin, joints, intestines, and kidneys. Although various infections and chemicals are known to be triggers, the underlying cause of IgAV remains unknown. Here, we describe a case of an 86-year-old male patient with IgAV that developed after anti-tuberculosis treatment for tuberculous pleurisy. There have been several case reports implicating and other acid-fast bacterium in the development of IgAV, but only a few case reports implicating anti-tuberculous drugs. This case highlights the importance of recognizing that IgAV can be caused by anti-tuberculous drugs.

摘要

免疫球蛋白A血管炎(IgAV),也称为过敏性紫癜(HSP),是一种导致皮肤、关节、肠道和肾脏中小血管炎症和出血的疾病。尽管已知各种感染和化学物质是触发因素,但IgAV的根本原因仍然未知。在此,我们描述一例86岁男性IgAV患者,该患者在结核性胸膜炎抗结核治疗后发病。已有几例病例报告表明分枝杆菌和其他抗酸菌与IgAV的发生有关,但仅有少数病例报告表明抗结核药物与之有关。该病例凸显了认识到抗结核药物可导致IgAV的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/659b/11109605/6ace530e2a21/cureus-0016-00000058707-i01.jpg

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